Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632703 | 0.82 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1CYP2C9CYP2C19 | |
| SCHEMBL17471375 | 0.81 | ALDH1A1 (0.53) | SLC1A3SLC1A2SLC1A1CYP2C9CYP2C19 | |
| SCHEMBL218320 | 0.79 | THRB (0.46) | KMT2AMEN1TSHRALDH1A1CYP3A4 | |
| SCHEMBL9650729 | 0.78 | TSHR (0.45) | KMT2AMEN1CYP1A2CYP2D6TSHR | |
| SCHEMBL17439436 | 0.77 | PPARG (0.42) | TSHRTHRB | |
| SCHEMBL3079998 | 0.77 | TSHR (0.48) | SLC1A3SLC1A2SLC1A1CYP2C9CYP2C19 | |
| SCHEMBL3390970 | 0.76 | TSHR (0.42) | CYP1A2TSHRALDH1A1THRBLMNA | |
| SCHEMBL1110901 | 0.76 | CYP3A4 (0.47) | TSHRALDH1A1CYP3A4THRBLMNA | |
| SCHEMBL237171 | 0.76 | TSHR (0.39) | TSHRALDH1A1CYP3A4THRBMAPK1 | |
| SCHEMBL28907212 | 0.75 | LMNA (0.39) | CYP2C19KMT2AMEN1TSHRHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673666-A1 | LOW-TACK, HYDROPHOBIC OPHTHALMIC DEVICE MATERIALS | Novartis AG (CH) | 2013-12-18 | — | — | EP | claimed |
| WO-2012109228-A1 | LOW-TACK, HYDROPHOBIC OPHTHALMIC DEVICE MATERIALS | NOVARTIS AG (CH) | 2012-08-16 | — | — | WO | claimed |