Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270697 | 0.87 | LMNA (0.74) | LMNAL3MBTL1KCNH2ALDH1A1POLB | |
| Water SCHEMBL10592152 | 0.84 | LMNA (0.61) | LMNAL3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL169675 | 0.81 | LMNA (0.68) | LMNAL3MBTL1KCNH2ALDH1A1POLB | |
| SCHEMBL81625 | 0.81 | LMNA (0.63) | LMNAL3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL31729500 | 0.81 | LMNA (0.68) | LMNAL3MBTL1KCNH2ALDH1A1POLB | |
| Benzene SCHEMBL27902631 | 0.81 | LMNA (0.63) | LMNAL3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL2950629 | 0.80 | LMNA (0.71) | LMNAL3MBTL1KCNH2ALDH1A1POLB | |
| Bromide SCHEMBL31469205 | 0.80 | LMNA (0.61) | LMNAL3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL30779764 | 0.80 | LMNA (0.61) | LMNAL3MBTL1ALDH1A1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL7143179 | 0.80 | L3MBTL1 (0.61) | LMNAL3MBTL1ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2672822-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | The Johns Hopkins University (US) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012109491-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-08-16 | — | — | WO | disclosed |