Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Procaterol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 16/20 | 0.98 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.98 |
| ▸ | MEN1 | O00255 | 1/20 | 0.98 |
| ▸ | LMNA | P02545 | 1/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.98 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.98 |
| ▸ | DRD2 | P14416 | 1/20 | 0.98 |
| ▸ | TSHR | P16473 | 1/20 | 0.98 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.98 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.98 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Procaterol SCHEMBL29992718 | 1.00 | KDM4E (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL9737339 | 1.00 | KDM4E (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL29832201 | 1.00 | KDM4E (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL27971156 | 0.99 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL29429700 | 0.99 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL1231478 | 0.99 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL29804927 | 0.99 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL1231477 | 0.99 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL4633 | 0.99 | ADRB2 (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL4632 | 0.99 | ADRB2 (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2088 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-223015046-U | Procaterol hydrochloride oral solution split charging device | 安徽瑞旗药业有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-119977883-A | Procaterol nitrosamine hydrochloride impurity as well as preparation method and application thereof | 淮安市第二人民医院 | 2025-05-13 | — | — | CN | claimed |
| CN-119679709-A | Procaterol hydrochloride liquid preparation and preparation method thereof | 成都倍特药业股份有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-119643739-A | Method for detecting relevant substances of procaterol hydrochloride oral solution | 广东稳健药业有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119606969-A | Pharmaceutical composition and application thereof | 九华华源药业(桂林)有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119595781-A | Method for measuring content of p-hydroxybenzoic acid in procaterol hydrochloride oral solution | 安徽环球药业股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-222567376-U | Procatluo hydrochloride oral solution processing equipment | 合肥远志医药科技开发有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119385988-A | Procaterol hydrochloride solution for inhalation and preparation method thereof | 深圳大佛药业股份有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-119384294-A | Anticholinergic agents and muscarinic agonists for the treatment of Demodex related conditions | 阿提莱普斯控股有限公司 | 2025-01-28 | — | — | CN | claimed |
| EP-3357945-B1 | ADHESIVE POLYMER AND MEDICAL ADHESIVE PATCH | TEIKOKU SEIYAKU KK (JP) | 2024-10-30 | — | — | EP | claimed |
| US-5626854-A | XANTHINE OR B-ADRENERGIC STIMULANT | KAO CORPORATION (JP) | 1997-05-06 | — | — | US | claimed |
| WO-1996031195-A1 | PACKAGE HOLDING A PROCATEROL HYDROCHLORIDE AQUEOUS SOLUTION FORMULATION, AND A PROCATEROL HYDROCHLORIDE AQUEOUS SOLUTION FORMULATION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-10 | — | — | WO | claimed |
| CN-1133004-A | Method for regulating substances | ASTRA AB (SE) | 1996-10-09 | — | — | CN | claimed |
| EP-0717616-A1 | PROCESS FOR CONDITIONING SUBSTANCES | Astra Aktiebolag (SE) | 1996-06-26 | — | — | EP | claimed |
| WO-1996004911-A1 | METHOD OF PREVENTING AND TREATING OPHTHALMIC INFLAMMATION AND/OR WOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-22 | — | — | WO | claimed |
| WO-1995005805-A1 | PROCESS FOR CONDITIONING SUBSTANCES | ASTRA AKTIEBOLAG (SE) | 1995-03-02 | — | — | WO | claimed |
| EP-0301589-B1 | PROCATEROL TRANSDERMAL DELIVERY SYSTEM | WARNER-LAMBERT COMPANY (US) | 1993-09-22 | — | — | EP | claimed |
| EP-0301589-A2 | Procaterol transdermal delivery system | WARNER-LAMBERT COMPANY (US) | 1989-02-01 | — | — | EP | claimed |
| US-4788064-A | PROCATEROL WITH FATTY ACID AND SOLVENTS SATURATE SPONGE HELD BETWEEN POROUS MEMBRANE AND BACKING | WARNER-LAMBERT COMPANY (US) | 1988-11-29 | — | — | US | claimed |
| US-4322425-A | ALKYL DERICVATIVES OF 5-/1-HYDROZXY-2-AMINOETHYL/-8-HYDROXYCARBOSTYRIL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-03-30 | — | — | US | claimed |