Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Procaterol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 16/20 | 0.98 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.98 |
| ▸ | MEN1 | O00255 | 1/20 | 0.98 |
| ▸ | LMNA | P02545 | 1/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.98 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.98 |
| ▸ | DRD2 | P14416 | 1/20 | 0.98 |
| ▸ | TSHR | P16473 | 1/20 | 0.98 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.98 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.98 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Procaterol SCHEMBL124726 | 1.00 | KDM4E (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL9737339 | 1.00 | KDM4E (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL29992718 | 1.00 | KDM4E (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL29429700 | 0.99 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL1231478 | 0.99 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL29804927 | 0.99 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL1231477 | 0.99 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL27971156 | 0.99 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL4632 | 0.99 | ADRB2 (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL4633 | 0.99 | ADRB2 (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115097050-A | Cleaning verification method for procaterol hydrochloride production equipment | 南京工业大学 | 2022-09-23 | — | — | CN | disclosed |