Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Procaterol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 16/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.98 |
| ▸ | GAA | P10253 | 1/20 | 0.98 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.98 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.98 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.95 |
| ▸ | MEN1 | O00255 | 1/20 | 0.95 |
| ▸ | LMNA | P02545 | 1/20 | 0.95 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.95 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.95 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.95 |
| ▸ | DRD2 | P14416 | 1/20 | 0.95 |
| ▸ | TSHR | P16473 | 1/20 | 0.95 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.95 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.95 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.95 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Procaterol SCHEMBL1231478 | 1.00 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL27971156 | 1.00 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL29804927 | 1.00 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL1231477 | 1.00 | KDM4E (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL29992718 | 0.99 | KDM4E (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL9737339 | 0.99 | KDM4E (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL29832201 | 0.99 | KDM4E (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL124726 | 0.99 | KDM4E (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL3244629 | 0.99 | ADRB2 (0.98) | KDM4EGAASMN1; SMN2HIF1AADRB2 | |
| Procaterol SCHEMBL4633 | 0.98 | ADRB2 (1.00) | KDM4EGAASMN1; SMN2HIF1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118033022-A | Method for measuring citric acid content in procaterol hydrochloride Luo Xiru solution | 南京华盖制药有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-116879427-A | Method for measuring relevant substances of procaterol hydrochloride oral solution | 深圳市贝美药业有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116879426-A | Method for measuring content of procaterol hydrochloride oral solution | 深圳市贝美药业有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116270454-A | Procaterol hydrochloride oral solution and preparation method thereof | 深圳市贝美药业有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-112198260-B | Method for detecting content of process impurities in procaterol hydrochloride medicinal preparation | 宜宾市南溪区红光制药有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-111239287-B | Method for detecting related substances in procaterol hydrochloride oral solution | 北京海泰天正医药科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-113143860-B | Procaterol hydrochloride oral solution | 江苏汉晨药业有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114452250-A | Procaterol hydrochloride oral liquid and preparation method thereof | 澳美制药(苏州)有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-113384540-B | Procaterol hydrochloride particle composition and preparation method thereof | 北京海泰天正医药科技有限公司 | 2022-04-01 | — | — | CN | disclosed |