Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | ACR | P10323 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12472031 | 0.97 | ADORA3 (0.54) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL21318616 | 0.97 | ADORA3 (0.54) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL13660272 | 0.89 | ADORA3 (0.46) | ADORA3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10046812 | 0.88 | ADORA3 (0.60) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL13660290 | 0.86 | ADORA3 (0.50) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL12352822 | 0.85 | ADORA3 (0.55) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL10084007 | 0.84 | ADORA3 (0.60) | ADORA3SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL253891 | 0.83 | ADORA3 (0.47) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL12352775 | 0.83 | ADORA3 (0.57) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL17814938 | 0.83 | MAPT (0.40) | TDP1L3MBTL1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985522-B2 | Electrophotographic photoreceptor | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-07-26 | — | — | US | disclosed |
| US-20110013934-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20090047589-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-02-19 | — | — | US | disclosed |