Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14274575 | 0.91 | ADORA3 (0.42) | ADORA3SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL12473086 | 0.86 | ADORA3 (0.57) | ADORA3SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL12134134 | 0.85 | ADORA3 (0.53) | ADORA3SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL13660272 | 0.84 | ADORA3 (0.46) | ADORA3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21318616 | 0.84 | ADORA3 (0.54) | ADORA3SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL12472031 | 0.84 | ADORA3 (0.54) | ADORA3SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL12473245 | 0.81 | PPARA (0.40) | ADORA3SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL12352775 | 0.80 | ADORA3 (0.57) | ADORA3SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL25797231 | 0.79 | KMT2A (0.56) | MAPTALDH1A1TP53THRBHTT | |
| SCHEMBL10068243 | 0.78 | ADORA3 (0.51) | ADORA3SLC6A2SLC6A4SLC6A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7604913-B2 | Electrophotographic photosensitive body | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20080063963-A1 | Electrophotographic Photosensitive Body | MITSUBISHI CHEMICAL CORPORATION (JP) | 2008-03-13 | — | — | US | disclosed |