Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473086 | 0.97 | ADORA3 (0.57) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL12472031 | 0.94 | ADORA3 (0.54) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL17814938 | 0.87 | MAPT (0.40) | TDP1SMN1; SMN2LMNATP53MAPT | |
| SCHEMBL13660272 | 0.86 | ADORA3 (0.46) | ADORA3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10046812 | 0.85 | ADORA3 (0.60) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL13660290 | 0.84 | ADORA3 (0.50) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL12352822 | 0.83 | ADORA3 (0.55) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL10084007 | 0.82 | ADORA3 (0.60) | ADORA3SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL253891 | 0.81 | ADORA3 (0.47) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL12352775 | 0.81 | ADORA3 (0.57) | ADORA3SLC6A2SLC6A4SLC6A3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190270846-A1 | POLYARYLATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2019-09-05 | — | — | US | disclosed |