Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473356 | 0.87 | KDM1A (0.49) | KDM1APOLBRAD52HTR2AKDM4E | |
| SCHEMBL12473279 | 0.83 | KDM1A (0.42) | KDM1AKDM4EMAPTMEN1JAK2 | |
| SCHEMBL12473443 | 0.81 | KDM4E (0.41) | POLBRAD52RXFP1HTR2AHTR2C | |
| SCHEMBL1289455 | 0.78 | RAD52 (0.59) | KDM1APOLBRAD52RXFP1KMT2A | |
| SCHEMBL12473328 | 0.77 | KMT2A (0.42) | HTR2AHTR2CHTR2BKDM4EMAPT | |
| SCHEMBL12473416 | 0.74 | KDM4E (0.46) | POLBRAD52RXFP1KDM4EMAPT | |
| SCHEMBL12473354 | 0.69 | KDM1A (0.49) | KDM1AATMALDH1A1LMNAHPGD | |
| SCHEMBL1289571 | 0.69 | ALDH1A1 (0.65) | KDM1APOLBRAD52RXFP1KMT2A | |
| Hydrochloric Acid SCHEMBL4511312 | 0.68 | ALDH1A1 (0.67) | KDM1APOLBRAD52RXFP1KMT2A | |
| SCHEMBL12473301 | 0.67 | APP (0.37) | HTR2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |