Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 3/20 | 0.49 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.49 |
| ▸ | TERT | O14746 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TRIM58 | Q8NG06 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289571 | 0.88 | ALDH1A1 (0.65) | RAD52POLBRXFP1FLT3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4511312 | 0.87 | ALDH1A1 (0.67) | RAD52POLBRXFP1FLT3ALDH1A1 | |
| SCHEMBL1687915 | 0.82 | RAD52 (0.72) | RAD52POLBRXFP1FLT3ALDH1A1 | |
| SCHEMBL1289424 | 0.81 | RAD52 (0.59) | RAD52POLBRXFP1FLT3ALDH1A1 | |
| SCHEMBL1289391 | 0.79 | RAD52 (0.59) | RAD52POLBRXFP1FLT3ALDH1A1 | |
| SCHEMBL12473282 | 0.78 | KDM1A (0.42) | RAD52POLBRXFP1ALDH1A1KDM1A | |
| Hydrochloric Acid SCHEMBL4507791 | 0.78 | RAD52 (0.61) | RAD52POLBRXFP1FLT3ALDH1A1 | |
| SCHEMBL1289551 | 0.77 | RAD52 (0.56) | RAD52POLBRXFP1FLT3ALDH1A1 | |
| SCHEMBL1289534 | 0.73 | RAD52 (0.67) | RAD52POLBRXFP1FLT3ALDH1A1 | |
| SCHEMBL12473279 | 0.72 | KDM1A (0.42) | ALDH1A1MAPK1KDM1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |