Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | ITK | Q08881 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 5/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | HTR1D | P28221 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 4/20 | 0.39 |
| ▸ | HTR5A | P47898 | 4/20 | 0.39 |
| ▸ | HTR1E | P28566 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473443 | 0.92 | KDM4E (0.41) | KMT2AKDM4EMEN1NPC1MAPT | |
| SCHEMBL12473416 | 0.92 | KDM4E (0.46) | KMT2AKDM4EMEN1NPC1MAPT | |
| SCHEMBL12473326 | 0.82 | KDM4E (0.42) | KMT2AKDM4EMEN1NPC1MAPT | |
| SCHEMBL12473301 | 0.79 | APP (0.37) | NPC1RAB9AHTR2CITK | |
| SCHEMBL1289551 | 0.77 | RAD52 (0.56) | KMT2AKDM4EMEN1MAPTLMNA | |
| SCHEMBL12473282 | 0.77 | KDM1A (0.42) | KMT2AKDM4EMEN1MAPTLMNA | |
| SCHEMBL12473440 | 0.75 | KDM4E (0.41) | KMT2AKDM4EMEN1NPC1MAPT | |
| SCHEMBL12473413 | 0.75 | KMT2A (0.46) | KMT2AKDM4EMEN1NPC1MAPT | |
| SCHEMBL1289534 | 0.74 | RAD52 (0.67) | KMT2AKDM4EMEN1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL4507613 | 0.73 | RAD52 (0.69) | KMT2AKDM4EMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |