Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | ITK | Q08881 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473413 | 0.87 | KMT2A (0.46) | ITKNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL12473440 | 0.87 | KDM4E (0.41) | ITKNPC1RAB9ATUBB4ATUBB | |
| SCHEMBL12473301 | 0.80 | APP (0.37) | APPITKNPC1RAB9ATUBB4A | |
| SCHEMBL12473326 | 0.79 | KDM4E (0.42) | ITKNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL12473354 | 0.78 | KDM1A (0.49) | APPNPC1RAB9AALDH1A1 | |
| SCHEMBL12473398 | 0.78 | PDE10A (0.37) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL12473414 | 0.72 | MAPT (0.35) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4509842 | 0.70 | ITK (0.36) | APPITKNPC1RAB9ATUBB4A | |
| SCHEMBL4496945 | 0.69 | NPC1 (0.49) | ITKNPC1RAB9ATUBB4ATUBB | |
| SCHEMBL12473350 | 0.69 | PDE10A (0.39) | NPC1RAB9AKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |