Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473326 | 0.92 | KDM4E (0.42) | KDM4EMAPTRAB9ANPC1DYRK3 | |
| SCHEMBL12473413 | 0.89 | KMT2A (0.46) | KDM4EMAPTRAB9ANPC1DYRK3 | |
| SCHEMBL12473298 | 0.87 | APP (0.37) | KDM4EMAPTRAB9ANPC1GSK3B | |
| SCHEMBL12473443 | 0.83 | KDM4E (0.41) | KDM4EMAPTRAB9ANPC1CASP3 | |
| SCHEMBL12473441 | 0.81 | KMT2A (0.42) | KDM4EMAPTCASP3SENP7DYRK3 | |
| SCHEMBL12473279 | 0.81 | KDM1A (0.42) | KDM4EMAPTRAB9ANPC1DYRK3 | |
| SCHEMBL12473328 | 0.75 | KMT2A (0.42) | KDM4EMAPTRAB9ANPC1DYRK3 | |
| SCHEMBL12473317 | 0.74 | KDM4E (0.42) | KDM4EMAPTRAB9ANPC1CASP3 | |
| SCHEMBL1289424 | 0.72 | RAD52 (0.59) | KDM4EMAPTGSK3BCLK4KMT2A | |
| SCHEMBL12473406 | 0.72 | CD74 (0.37) | KDM4EMAPTRAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |