Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ITK | Q08881 | 3/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473326 | 0.92 | KDM4E (0.42) | KMT2AKDM4EMAPTMEN1NPC1 | |
| SCHEMBL12473440 | 0.89 | KDM4E (0.41) | KMT2AKDM4EMAPTMEN1NPC1 | |
| SCHEMBL12473298 | 0.87 | APP (0.37) | KMT2AKDM4EMAPTMEN1NPC1 | |
| SCHEMBL12473416 | 0.83 | KDM4E (0.46) | KMT2AKDM4EMAPTMEN1NPC1 | |
| SCHEMBL12473328 | 0.75 | KMT2A (0.42) | KMT2AKDM4EMAPTMEN1NPC1 | |
| SCHEMBL12473441 | 0.74 | KMT2A (0.42) | KMT2AKDM4EMAPTMEN1CNR2 | |
| SCHEMBL12473317 | 0.74 | KDM4E (0.42) | KMT2AKDM4EMAPTMEN1NPC1 | |
| SCHEMBL12473279 | 0.74 | KDM1A (0.42) | KMT2AKDM4EMAPTMEN1NPC1 | |
| SCHEMBL1289534 | 0.72 | RAD52 (0.67) | KMT2AKDM4EMAPTMEN1CYP1A2 | |
| SCHEMBL12473443 | 0.72 | KDM4E (0.41) | KMT2AKDM4EMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |