SCHEMBL12474635

SCHEMBL12474635

NOC1CCC2(CC1)OCCO2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL600923 0.76 DPP4 (0.34)
SCHEMBL372402 0.72 LMNA (0.32)
SCHEMBL18355787 0.71
SCHEMBL606430 0.71
SCHEMBL20843821 0.71
SCHEMBL601379 0.71 LMNA (0.33)
SCHEMBL600539 0.71
Hydrochloric Acid SCHEMBL31095712 0.70 LMNA (0.31)
SCHEMBL24837641 0.70
SCHEMBL604240 0.70 JAK2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2704568-B1 DIAZENIUMDIOLATE CYCLOHEXYL DERIVATIVES MERCK SHARP & DOHME (US) 2018-01-24 EP disclosed
WO-2012111995-A1 OXIME DERIVATIVES AS GPR119 AGONISTS LG LIFE SCIENCES LTD. (KR) 2012-08-23 WO disclosed