Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31095712 | 0.97 | LMNA (0.31) | LMNAMAPK1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL10893950 | 0.90 | — | — | |
| SCHEMBL18610919 | 0.84 | — | — | |
| SCHEMBL11820421 | 0.81 | — | — | |
| SCHEMBL15326795 | 0.75 | — | — | |
| SCHEMBL11816666 | 0.74 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL24424198 | 0.72 | — | — | |
| SCHEMBL2631205 | 0.72 | — | — | |
| SCHEMBL662249 | 0.72 | — | — | |
| SCHEMBL24340232 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674846-A1 | UREA MOTIF CONTAINING COMPOUNDS AS ANTIBACTERIAL DRUGS AGAINST MULTIRESISTANT MYCOBACTERIA | Technische Universität München (DE) | 2026-01-07 | — | — | EP | claimed |
| EP-1742925-B1 | SUBSTITUTED 5, 6, 7, 8-TETRAHYDRO-PYRIDO[4, 3-D]PYRIMIDINE-2-YL COMPOUNDS AND 5, 6, 7, 8-TETRAHYDRO-QUINAZOLINE-2-YL COMPOUNDS | GRUENENTHAL GMBH (DE) | 2014-04-23 | — | — | EP | claimed |
| EP-1542981-B1 | PROCESS FOR THE PREPARATION OF 2-AMINO-4,5,6,7-TETRAHYDRO-6-AMINOBENZOTHIAZOLES FROM CYCLOHEXANES AND CYCLOHEXANONES AS INTERMEDIATES | GENERICS UK LTD (GB) | 2009-07-22 | — | — | EP | claimed |
| US-20070249631-A1 | Substituted 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2-yl compounds and 5,6,7,8-tetrahydroquinazoline-2-yl compounds | GRUENENTHAL GMBH (DE) | 2007-10-25 | — | — | US | claimed |
| EP-1444206-B1 | SUBSTITUTED BENZO[B]AZEPIN-2-ONE COMPOUNDS AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2006-03-15 | — | — | EP | claimed |
| EP-1542981-A1 | PROCESS FOR THE PREPARATION OF 2-AMINO-4,5,6,7-TETRAHYDRO-6-AMINOBENZOTHIAOLES FROM CYCLOHEXANES AND CYCLOHEXANONES AS INTERMEDIATES | Generics (UK) Limited (GB) | 2005-06-22 | — | — | EP | claimed |
| JP-2005511570-A | — | — | 2005-04-28 | — | — | JP | claimed |
| JP-2005511566-A | — | — | 2005-04-28 | — | — | JP | claimed |
| EP-1472221-A2 | SUBSTITUTED INDOLES, METHOD FOR PRODUCTION AND USE THEREOF FOR THE INHIBITION OF PAIN | Grünenthal GmbH (DE) | 2004-11-03 | — | — | EP | claimed |
| EP-1444212-A1 | SUBSTITUTED (1H)-QUINOXALIN-2-ONE COMPOUNDS AND SUBSTITUTED 4-ARYL- AND 4-HETEROARYLCYCLOHEXANE COMPOUNDS | Grünenthal GmbH (DE) | 2004-08-11 | — | — | EP | claimed |
| EP-1444206-A1 | SUBSTITUTED BENZO B AZEPIN-2-ONE COMPOUNDS | Grünenthal GmbH (DE) | 2004-08-11 | — | — | EP | claimed |
| EP-1442021-A1 | SUBSTITUTED 1H-QUINOLIN-2-ONE COMPOUNDS | Grünenthal GmbH (DE) | 2004-08-04 | — | — | EP | claimed |
| WO-2004026850-A1 | PROCESS FOR THE PREPARATION OF 2-AMINO-4,5,6,7-TETRAHYDRO-6-AMINOBENZOTHIAOLES FROM CYCLOHEXANES AND CYCLOHEXANONES AS INTERMEDIATES | GENERICS [UK] LIMITED (GB) | 2004-04-01 | — | — | WO | claimed |
| WO-2003037870-A1 | SUBSTITUTED 1H-QUINOLIN-2-ONE COMPOUNDS | Grünenthal GmbH (DE) | 2003-05-08 | — | — | WO | claimed |
| WO-2003037873-A1 | SUBSTITUTED BENZO[B]AZEPIN-2-ONE COMPOUNDS | Grünenthal GmbH (DE) | 2003-05-08 | — | — | WO | claimed |
| WO-2003037863-A2 | SUBSTITUTED INDOLES, METHOD FOR PRODUCTION AND USE THEREOF FOR THE INHIBITION OF PAIN | Grünenthal GmbH (DE) | 2003-05-08 | — | — | WO | claimed |
| WO-2003037879-A1 | SUBSTITUTED (1H)-QUINOXALIN-2-ONE COMPOUNDS AND SUBSTITUTED 4-ARYL- AND 4-HETEROARYLCYCLOHEXANE COMPOUNDS | Grünenthal GmbH (DE) | 2003-05-08 | — | — | WO | claimed |
| US-4652559-A | ANALGESIC, ANTIDEPRESSANT | THE UPJOHN COMPANY (US) | 1987-03-24 | — | — | US | claimed |
| EP-0085811-B1 | 2-(PHENYLMETHYLENE)CYCLOALKYLAMINES | THE UPJOHN COMPANY (US) | 1986-05-07 | — | — | EP | claimed |
| EP-0085811-A1 | 2-(Phenylmethylene)cycloalkylamines | THE UPJOHN COMPANY (US) | 1983-08-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249631-A1 | Substituted 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2-yl compounds and 5,6,7,8-tetrahydroquinazoline-2-yl compounds | P2RX7, CYP2C8, P2RX5 | LMNA 3096/4885MAPK1 3297/4885ALDH1A1 772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.