Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475113 | 1.00 | MCHR1 (0.32) | MCHR1LNPEPERAP2ERAP1UTS2R | |
| SCHEMBL12475177 | 0.91 | MCHR1 (0.33) | MCHR1LNPEPERAP2ERAP1UTS2R | |
| SCHEMBL12475169 | 0.91 | MCHR1 (0.33) | MCHR1LNPEPERAP2ERAP1UTS2R | |
| SCHEMBL12475086 | 0.91 | KIF11 (0.33) | MCHR1LNPEPERAP2ERAP1UTS2R | |
| SCHEMBL12475079 | 0.91 | KIF11 (0.33) | MCHR1LNPEPERAP2ERAP1UTS2R | |
| SCHEMBL12475210 | 0.88 | MCHR1 (0.33) | MCHR1UTS2R | |
| SCHEMBL12475228 | 0.88 | MCHR1 (0.33) | MCHR1UTS2R | |
| SCHEMBL12475049 | 0.87 | CTNNB1 (0.33) | MCHR1UTS2R | |
| SCHEMBL12475046 | 0.87 | CTNNB1 (0.33) | MCHR1UTS2R | |
| SCHEMBL12475167 | 0.87 | LNPEP (0.33) | MCHR1LNPEPERAP2ERAP1UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673281-B1 | BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTICS USES THEREOF | REMPEX PHARMACEUTICALS INC (US) | 2016-04-13 | — | — | EP | disclosed |
| EP-2673281-B1 | BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTICS USES THEREOF | REMPEX PHARMACEUTICALS INC (US) | 2016-04-13 | — | — | EP | disclosed |
| US-8933018-B2 | Boron containing polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2015-01-13 | — | — | US | disclosed |
| US-8933018-B2 | Boron containing polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2015-01-13 | — | — | US | disclosed |
| EP-2673281-A1 | BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTICS USES THEREOF | Rempex Pharmaceuticals, Inc. (US) | 2013-12-18 | — | — | EP | disclosed |
| US-20130316943-A1 | BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | REMPEX PHARMACEUTICALS, INC. (US) | 2013-11-28 | — | — | US | disclosed |
| WO-2012109164-A1 | BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTICS USES THEREOF | REMPEX PHARMACEUTICALS, INC. (US) | 2012-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130316943-A1 | BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCB1, SLC47A1 | MCHR1 2689/4885LNPEP 593/4885ERAP2 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.