Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864853 | 0.83 | ALDH1A1 (0.33) | KDM4EALDH1A1POLBMAPTTSHR | |
| SCHEMBL12475270 | 0.77 | — | — | |
| SCHEMBL12475125 | 0.77 | — | — | |
| SCHEMBL8054703 | 0.71 | CA1 (0.30) | — | |
| SCHEMBL1177456 | 0.70 | — | — | |
| SCHEMBL9700492 | 0.69 | EGLN1 (0.33) | KDM4EPOLBTSHR | |
| SCHEMBL8161986 | 0.68 | MAPT (0.45) | MAPT | |
| SCHEMBL7350816 | 0.68 | SLC6A3 (0.44) | KDM4EALDH1A1POLBMAPTTSHR | |
| SCHEMBL5911681 | 0.68 | KMT2A (0.49) | ALDH1A1POLBMAPTTSHR | |
| SCHEMBL11304206 | 0.67 | ALDH1A1 (0.59) | KDM4EALDH1A1POLBMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673272-A1 | MICROBIOCIDAL PYRAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107477-A1 | MICROBIOCIDAL PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-08-16 | — | — | WO | disclosed |