Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134592 | 0.85 | LMNA (0.41) | ALDH1A1MAPTP2RX7NPSR1RAB9A | |
| SCHEMBL9240067 | 0.84 | HPD (0.46) | SMN1; SMN2TSHRALDH1A1MAPK1POLB | |
| SCHEMBL10815118 | 0.82 | SMN1; SMN2 (0.53) | SLC6A3SMN1; SMN2TSHRCASP1ALDH1A1 | |
| SCHEMBL7344969 | 0.79 | TSHR (0.50) | SMN1; SMN2TSHRCASP1ALDH1A1MAPK1 | |
| SCHEMBL2904657 | 0.76 | LMNA (0.33) | ALDH1A1 | |
| SCHEMBL9430636 | 0.75 | TSHR (0.42) | SLC6A3SMN1; SMN2TSHRCASP1ALDH1A1 | |
| SCHEMBL9874230 | 0.74 | P2RX7 (0.49) | SLC6A3SMN1; SMN2TSHRCASP1ALDH1A1 | |
| SCHEMBL6772082 | 0.74 | — | — | |
| SCHEMBL9814786 | 0.74 | SMN1; SMN2 (0.47) | SLC6A3SMN1; SMN2TSHRCASP1ALDH1A1 | |
| SCHEMBL9711583 | 0.73 | SMN1; SMN2 (0.44) | SLC6A3SMN1; SMN2TSHRCASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5085688-A | Certain 2-(2-chloro-3-alkoxy-4-substituted benzoyl)-5-methyl-5-1,3-cyclohexanediones as herbicides | ICI AMERICAS INC. (US) | 1992-02-04 | — | — | US | disclosed |
| US-5006158-A | Herbicides | ICI AMERICAS INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4946981-A | HERBICIDES | ICI AMERICAS INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4853028-A | Certain 2-(2-substituted benzoyl)-1,3-cyclohexanediones | STAUFFER CHEMICAL COMPANY (US) | 1989-08-01 | — | — | US | disclosed |
| US-4822906-A | HERBICIDE INTERMEDIATE | STAUFFER CHEMICAL COMPANY (US) | 1989-04-18 | — | — | US | disclosed |
| US-4816066-A | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1989-03-28 | — | — | US | disclosed |
| US-4806146-A | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| US-4780127-A | Certain 2-(substituted benzoyl)-1,3-cyclohexanediones and their use as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1988-10-25 | — | — | US | disclosed |