Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475469 | 0.81 | MMP9 (0.47) | MMP9MMP8MMP1CTSLCTSS | |
| SCHEMBL12475471 | 0.78 | MMP9 (0.44) | MMP9MMP8MMP1CTSLCTSS | |
| SCHEMBL19520887 | 0.76 | MMP9 (0.62) | MMP9MMP8MMP1LMNA | |
| SCHEMBL19520888 | 0.76 | MMP9 (0.62) | MMP9MMP8MMP1LMNA | |
| SCHEMBL24814066 | 0.76 | MMP1 (0.59) | MMP9MMP8MMP1MEN1LMNA | |
| SCHEMBL27258437 | 0.76 | MMP9 (0.51) | MMP9MMP8MMP1CTSLCTSS | |
| SCHEMBL19520895 | 0.75 | MMP9 (0.55) | MMP9MMP8MMP1MEN1LMNA | |
| SCHEMBL19520896 | 0.75 | MMP9 (0.55) | MMP9MMP8MMP1MEN1LMNA | |
| SCHEMBL12537192 | 0.73 | MMP9 (0.54) | MMP9MMP8MMP1LMNA | |
| SCHEMBL25553328 | 0.73 | CTSS (0.49) | MMP9MMP8CTSLCTSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012108990-A2 | PEPTIDE-PHOSPHOLIPID CONJUGATES | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2012-08-16 | — | — | WO | disclosed |