⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3326747 | 0.80 | — | — | |
| Iodide SCHEMBL10525742 | 0.79 | — | — | |
| SCHEMBL3327750 | 0.72 | — | — | |
| SCHEMBL1719585 | 0.69 | ALDH1A1 (0.30) | — | |
| Isobutane SCHEMBL28943382 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL1717892 | 0.67 | — | — | |
| SCHEMBL1718325 | 0.67 | — | — | |
| Tert-Butanol SCHEMBL384629 | 0.65 | — | — | |
| Isobutane SCHEMBL909720 | 0.65 | — | — | |
| SCHEMBL15955554 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027596-B1 | COMPOUNDS CONTAINING A PENTALENE UNIT AND PROCESS FOR THEIR PREPARATION | ENI SPA (IT) | 2018-11-21 | — | — | EP | claimed |
| EP-2828260-B9 | PROCESS FOR THE PREPARATION OF TETRACARBOXYNAPHTHALENEDIIMIDE COMPOUNDS DISUBSTITUTED WITH HETEROARYL GROUPS | ENI SPA (IT) | 2018-03-14 | — | — | EP | claimed |
| EP-2828260-B1 | PROCESS FOR THE PREPARATION OF TETRACARBOXYNAPHTHALENEDIIMIDE COMPOUNDS DISUBSTITUTED WITH HETEROARYL GROUPS | ENI SPA (IT) | 2017-11-29 | — | — | EP | claimed |
| US-9776984-B2 | Compounds containing a pentalene unit and process for their preparation | ENI S.P.A. (IT) | 2017-10-03 | — | — | US | claimed |
| US-20160090371-A1 | COMPOUNDS CONTAINING A PENTALENE UNIT AND PROCESS FOR THEIR PREPARATION | ENI S.P.A. (IT) | 2016-03-31 | — | — | US | claimed |
| US-9000170-B2 | Process for the preparation of tetracarboxynaphthalenediimide compounds disubstituted with heteroaryl groups | ENI S.P.A. (IT) | 2015-04-07 | — | — | US | claimed |
| US-20150051398-A1 | PROCESS FOR THE PREPARATION OF TETRACARBOXYNAPHTHALENEDIIMIDE COMPOUNDS DISUBSTITUTED WITH HETEROARYL GROUPS | ENI S.P.A. (IT) | 2015-02-19 | — | — | US | claimed |
| EP-3027596-B1 | COMPOUNDS CONTAINING A PENTALENE UNIT AND PROCESS FOR THEIR PREPARATION | ENI SPA (IT) | 2018-11-21 | — | — | EP | disclosed |
| EP-2828260-B9 | PROCESS FOR THE PREPARATION OF TETRACARBOXYNAPHTHALENEDIIMIDE COMPOUNDS DISUBSTITUTED WITH HETEROARYL GROUPS | ENI SPA (IT) | 2018-03-14 | — | — | EP | disclosed |
| EP-2828260-B1 | PROCESS FOR THE PREPARATION OF TETRACARBOXYNAPHTHALENEDIIMIDE COMPOUNDS DISUBSTITUTED WITH HETEROARYL GROUPS | ENI SPA (IT) | 2017-11-29 | — | — | EP | disclosed |
| US-9776984-B2 | Compounds containing a pentalene unit and process for their preparation | ENI S.P.A. (IT) | 2017-10-03 | — | — | US | disclosed |
| US-20160090371-A1 | COMPOUNDS CONTAINING A PENTALENE UNIT AND PROCESS FOR THEIR PREPARATION | ENI S.P.A. (IT) | 2016-03-31 | — | — | US | disclosed |
| US-9000170-B2 | Process for the preparation of tetracarboxynaphthalenediimide compounds disubstituted with heteroaryl groups | ENI S.P.A. (IT) | 2015-04-07 | — | — | US | disclosed |
| US-20150051398-A1 | PROCESS FOR THE PREPARATION OF TETRACARBOXYNAPHTHALENEDIIMIDE COMPOUNDS DISUBSTITUTED WITH HETEROARYL GROUPS | ENI S.P.A. (IT) | 2015-02-19 | — | — | US | disclosed |
| WO-2012090219-A2 | THIAZOLE COMPOUNDS USEFUL AS ACETYL-COA CARBOXYLASE (ACC) INHIBITORS | JUBILANT BIOSYS LTD. (IN) | 2012-07-05 | — | — | WO | disclosed |