Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699054 | 0.81 | NPC1 (0.42) | NOS1POLBALDH1A1NPC1MAPT | |
| SCHEMBL2655449 | 0.79 | TEAD4 (0.47) | NOS1POLBALDH1A1NPC1MAPT | |
| SCHEMBL3772542 | 0.79 | GAA (0.50) | NOS1POLBALDH1A1NPC1MAPT | |
| SCHEMBL184686 | 0.78 | CYP19A1 (0.44) | POLBALDH1A1MYCWDR5NPC1 | |
| SCHEMBL10329778 | 0.76 | MAP4K4 (0.43) | NOS1POLBALDH1A1NPC1MAPT | |
| SCHEMBL184691 | 0.75 | ALDH1A1 (0.47) | POLBALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL2667227 | 0.72 | POLB (0.36) | NOS1POLBALDH1A1NPC1MAPT | |
| SCHEMBL210658 | 0.72 | LMNA (0.49) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL12476000 | 0.72 | POLB (0.42) | NOS1POLBALDH1A1NPC1MAPT | |
| SCHEMBL12475998 | 0.72 | TSHR (0.54) | POLBALDH1A1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012090219-A2 | THIAZOLE COMPOUNDS USEFUL AS ACETYL-COA CARBOXYLASE (ACC) INHIBITORS | JUBILANT BIOSYS LTD. (IN) | 2012-07-05 | — | — | WO | disclosed |