Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12341798 | 0.85 | ACHE (0.52) | SLC13A5ACHEALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL697285 | 0.84 | ACHE (0.56) | SLC13A5ACHEALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL3620118 | 0.82 | ACHE (0.54) | SLC13A5ACHEALDH1A1CYP3A4ADRA1A | |
| SCHEMBL18894529 | 0.81 | SLC6A2 (0.49) | ALDH1A1ADRA1ATAAR1GAAMEN1 | |
| SCHEMBL1145887 | 0.81 | ADRA1A (0.68) | ADRA1ATAAR1 | |
| SCHEMBL8708761 | 0.81 | TAAR1 (0.68) | ADRA1ATAAR1 | |
| SCHEMBL30546634 | 0.81 | TAAR1 (0.68) | ADRA1ATAAR1 | |
| SCHEMBL11288361 | 0.79 | ACHE (0.60) | SLC13A5ACHEALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL6044488 | 0.79 | KDM4E (0.53) | ALDH1A1L3MBTL1MAPTGAALMNA | |
| SCHEMBL27685404 | 0.79 | MAPT (0.52) | ALDH1A1CYP3A4ADRA1ATAAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012090219-A2 | THIAZOLE COMPOUNDS USEFUL AS ACETYL-COA CARBOXYLASE (ACC) INHIBITORS | JUBILANT BIOSYS LTD. (IN) | 2012-07-05 | — | — | WO | disclosed |