Sugi Predict

Sugi Predict / Compounds / SCHEMBL697285

SCHEMBL697285

SCHEMBL697285

COc1ccc(C)cc1CO

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 1/20 0.56
▸ ALDH1A1 P00352 2/20 0.50
▸ PDE4A P27815 1/20 0.50
▸ PDE4B Q07343 1/20 0.50
▸ PDE4C Q08493 1/20 0.50
▸ PDE4D Q08499 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ SLC13A5 Q86YT5 1/20 0.48
▸ L3MBTL1 Q9Y468 3/20 0.45
▸ MAPT P10636 2/20 0.45
▸ MAPK1 P28482 2/20 0.45
▸ GAA P10253 2/20 0.45
▸ LMNA P02545 1/20 0.45
▸ TSHR P16473 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ PDCD1 Q15116 1/20 0.44
▸ CD274 Q9NZQ7 1/20 0.44
▸ MEN1 O00255 1/20 0.43
▸ USP2 O75604 1/20 0.43
▸ POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13220234 0.85 PDCD1 (0.46) ACHEALDH1A1PDE4APDE4BPDE4C
SCHEMBL12476293 0.84 SLC13A5 (0.52) ACHEALDH1A1CYP3A4SLC13A5L3MBTL1
SCHEMBL703143 0.83 PDCD1 (0.56) ACHEALDH1A1PDE4APDE4BPDE4C
SCHEMBL11288361 0.83 ACHE (0.60) ACHEALDH1A1CYP3A4SLC13A5L3MBTL1
SCHEMBL11718647 0.82 MAPT (0.44) ACHEALDH1A1PDE4APDE4BPDE4C
SCHEMBL12259237 0.81 ACHE (0.48) ACHEALDH1A1PDE4APDE4BPDE4C
SCHEMBL8282401 0.81 ACHE (0.58) ACHEALDH1A1CYP3A4SLC13A5L3MBTL1
SCHEMBL12527285 0.80 MAPT (0.57) ALDH1A1L3MBTL1MAPTMAPK1GAA
SCHEMBL806312 0.80 PDE4A (0.61) ACHEALDH1A1PDE4APDE4BPDE4C
SCHEMBL18124818 0.79 MAPT (0.49) ACHEALDH1A1SLC13A5L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005003140-A1 4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2005-01-13 — — WO claimed
US-20050004161-A1 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents AGOURON PHARMACEUTICALS, INC. 2005-01-06 — — US claimed
CN-119768741-A Positive photosensitive resin composition 日产化学株式会社 2025-04-04 — — CN disclosed
CN-119604817-A Positive photosensitive resin composition 日产化学株式会社 2025-03-11 — — CN disclosed
CN-118388351-A Method for synthesizing N-alkylated amine by metal carbide hydrogen transfer catalysis 江南大学 2024-07-26 — — CN disclosed
CN-118192168-A Photosensitive resin composition 日产化学株式会社 2024-06-14 — — CN disclosed
CN-110537146-B Photosensitive resin composition 日产化学株式会社 2024-03-15 — — CN disclosed
CN-110537147-B Photosensitive resin composition 日产化学株式会社 2024-03-12 — — CN disclosed
CN-110573963-B Photosensitive resin composition 日产化学株式会社 2023-10-24 — — CN disclosed
CN-116848466-A Positive photosensitive resin composition 日产化学株式会社 2023-10-03 — — CN disclosed
CN-110291849-B Wiring forming method 日产化学株式会社 2023-06-06 — — CN disclosed
US-20070167506-A1 SUBSTITUTED IMIDAZOLES PFIZER INC. (US) 2007-07-19 — — US disclosed
EP-1728792-A1 8-OXOADENINE COMPOUND Dainippon Sumitomo Pharma Co., Ltd. (JP) 2006-12-06 — — EP disclosed
US-20050171049-A1 Compounds for the treatment of ischemia DENINNO MICHAEL P (US) 2005-08-04 — — US disclosed
WO-2005003140-A1 4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2005-01-13 — — WO disclosed
US-20050004161-A1 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents AGOURON PHARMACEUTICALS, INC. 2005-01-06 — — US disclosed
US-20040220194-A1 2-Alkynyl-and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists SCHERING CORPORATION 2004-11-04 — — US disclosed
US-20040220194-A1 2-Alkynyl-and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists SCHERING CORPORATION 2004-11-04 — — US disclosed
US-20030055021-A1 Compounds for the treatment of ischemia PFIZER, INC. 2003-03-20 — — US disclosed
EP-1241176-A1 Purine derivatives for the treatment of ischemia Pfizer Products Inc. (US) 2002-09-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050171049-A1 Compounds for the treatment of ischemia TNNI3, ADRB3, TBXA2R ACHE 3396/4885ALDH1A1 209/4885PDE4A 53/4885
US-20050004161-A1 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents ZC3HAV1, IRF3, BRD4 ACHE 3386/4885ALDH1A1 943/4885PDE4A 293/4885
US-20030055021-A1 Compounds for the treatment of ischemia TNNI3, ADRB3, FABP3 ACHE 2844/4885ALDH1A1 378/4885PDE4A 47/4885
US-20040220194-A1 2-Alkynyl-and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists ADORA2A, ADORA3, ADORA1 ACHE 634/4885ALDH1A1 591/4885PDE4A 463/4885
US-20070167506-A1 SUBSTITUTED IMIDAZOLES ABL1, TYR, CYP3A4 ACHE 230/4885ALDH1A1 617/4885PDE4A 726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.