Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.91 |
| ▸ | HPGD | P15428 | 6/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.91 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL6249450 | 0.97 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL546852 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL7738091 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL11599872 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL458273 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL9981 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL11514957 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL3132735 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL1026592 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL6934680 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4423168-B1 | POLYETHER POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-12-10 | — | — | EP | disclosed |
| US-20250115711-A1 | POLYETHER POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-04-10 | — | — | US | disclosed |
| US-12201971-B2 | Polyether polymerization process | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-01-21 | — | — | US | disclosed |
| US-20240392068-A1 | POLYETHER POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-11-28 | — | — | US | disclosed |
| US-12152104-B2 | Polyether polymerization process | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-11-26 | — | — | US | disclosed |
| EP-4423170-A2 | POLYETHER POLYMERIZATION PROCESS | Dow Global Technologies LLC (US) | 2024-09-04 | — | — | EP | disclosed |
| EP-4423168-A1 | POLYETHER POLYMERIZATION PROCESS | Dow Global Technologies LLC (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-118043376-A | Polyether polymerization process | 陶氏环球技术有限责任公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-118043375-A | Polyether polymerization process | 陶氏环球技术有限责任公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-113195591-B | Polyether polymerization process | 陶氏环球技术有限责任公司 | 2024-05-07 | — | — | CN | disclosed |
| US-9556309-B2 | Alkylene oxide polymerization using a double metal cyanide catalyst complex and a magnesium, group 3-group 15 metal or lanthanide series metal compound | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-01-31 | — | — | US | disclosed |
| US-9139506-B2 | Process for making hybrid polyester-polyether polyols | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150225504-A1 | ALKYLENE OXIDE POLYMERIZATION USING A DOUBLE METAL CYANIDE CATALYST COMPLEX AND A MAGNESIUM, GROUP 3 - GROUP 15 METAL OR LANTHANIDE SERIES METAL COMPOUND | DOW BENELUX B.V. (NL) | 2015-08-13 | — | — | US | disclosed |
| US-9040657-B2 | Alkylene oxide polymerization using a double metal cyanide catalyst complex and a magnesium, Group 3-Group 15 metal or lanthanide series metal compound | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-05-26 | — | — | US | disclosed |
| US-20140357887-A1 | Process for Making Hybrid Polyester-Polyether Polyols | DOW BENELUX B.V. (NL) | 2014-12-04 | — | — | US | disclosed |
| EP-2791203-A2 | PROCESS FOR MAKING HYBRID POLYESTER-POLYETHER POLYOLS | Dow Global Technologies LLC (US) | 2014-10-22 | — | — | EP | disclosed |
| EP-2658895-A1 | ALKYLENE OXIDE POLYMERIZATION USING A DOUBLE METAL CYANIDE CATALYST COMPLEX AND A MAGNESIUM, GROUP 3-GROUP 15 METAL OR LANTHANIDE SERIES METAL COMPOUND | Dow Global Technologies LLC (US) | 2013-11-06 | — | — | EP | disclosed |
| US-20130289236-A1 | ALKYLENE OXIDE POLYMERIZATION USING A DOUBLE METAL CYANIDE CATALYST COMPLEX AND A MAGNESIUM, GROUP 3 - GROUP 15 METAL OR LANTHANIDE SERIES METAL COMPOUND | DOW BENELUX B.V. (NL) | 2013-10-31 | — | — | US | disclosed |
| WO-2013095976-A2 | PROCESS FOR MAKING HYBRID POLYESTER-POLYETHER POLYOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-27 | — | — | WO | disclosed |
| WO-2012091968-A1 | ALKYLENE OXIDE POLYMERIZATION USING A DOUBLE METAL CYANIDE CATALYST COMPLEX AND A MAGNESIUM, GROUP 3-GROUP 15 METAL OR LANTHANIDE SERIES METAL COMPOUND | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-07-05 | — | — | WO | disclosed |