Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.91 |
| ▸ | HPGD | P15428 | 6/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.91 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL6249450 | 0.97 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL458273 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL6934680 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL11599872 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL9981 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL3132735 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL1026592 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL11514957 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL12477385 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL7205746 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119505316-A | Manufacturing method of anti-tearing temperature-resistant CPP film for electronic screen protection | 南通苍峰新材料科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| EP-3802752-B1 | METHOD FOR PREVENTING OR REDUCING LOW SPEED PRE-IGNITION IN DIRECT INJECTED SPARK-IGNITED ENGINES WITH MANGANESE-CONTAINING LUBRICANT | CHEVRON USA INC (US) | 2023-07-19 | — | — | EP | claimed |
| CN-112368361-B | Method of preventing or reducing low speed pre-ignition in a direct injection spark ignition engine with a manganese-containing lubricant | 雪佛龙美国公司 | 2022-11-01 | — | — | CN | claimed |
| EP-3802752-A1 | METHOD FOR PREVENTING OR REDUCING LOW SPEED PRE-IGNITION IN DIRECT INJECTED SPARK-IGNITED ENGINES WITH MANGANESE-CONTAINING LUBRICANT | Chevron U.S.A. Inc. (US) | 2021-04-14 | — | — | EP | claimed |
| CN-112368361-A | Method of preventing or reducing low speed pre-ignition in a direct injection spark ignition engine with a manganese-containing lubricant | 雪佛龙美国公司 | 2021-02-12 | — | — | CN | claimed |
| CN-108417795-B | Preparation method of transition metal/transition metal carbodiimide composite material | 陕西科技大学 | 2020-11-27 | — | — | CN | claimed |
| WO-2018231782-A2 | METAL COMPLEXES AS PHARMACEUTICALS FOR TREATMENT AND PREVENTION OF CANCER AND INFLAMMATORY DISEASES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2018-12-20 | — | — | WO | claimed |
| US-20180353539-A1 | METAL COMPLEXES AS PHARMACEUTICALS FOR TREATMENT AND PREVENTION OF CANCER AND INFLAMMATORY DISEASES | UNIV SOUTHERN CALIFORNIA (US) | 2018-12-13 | — | — | US | claimed |
| CN-108417795-A | A kind of preparation method of transition metal/transition metal carbodiimide composite material | 陕西科技大学 | 2018-08-17 | — | — | CN | claimed |
| US-9717939-B2 | Fire extinguishing composition containing transition metal compound | XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD (CN) | 2017-08-01 | — | — | US | claimed |
| EP-1431372-A2 | Use of manganese compounds to inhibit both low- and high-temperature corrosion in utility and industrial furnace systems | ETHYL CORPORATION (US) | 2004-06-23 | — | — | EP | claimed |
| CN-1506614-A | Transfer of manganese from lubricant source to fuel combustion system | 乙基公司 | 2004-06-23 | — | — | CN | claimed |
| US-20040110104-A1 | Delivering manganese from a lubricant source into a fuel combustion system | AFTON CHEMICAL INTANGIBLES LLC | 2004-06-10 | — | — | US | claimed |
| US-20040105894-A1 | Trace Metals synergized copper nucleotides and copper glycosides for anti-aging and antiviral compositions | GUPTA SHYAM K (US) | 2004-06-03 | — | — | US | claimed |
| US-6136292-A | Determination of non-functioning areas of the g.i. tract using MRI of manganese composition | NYCOMED IMAGING AS (NO) | 2000-10-24 | — | — | US | claimed |
| US-6120756-A | REDUCE SEBUM | Markowitz, Philip I. (US) | 2000-09-19 | — | — | US | claimed |
| EP-0941127-A2 | METHOD | NYCOMED IMAGING AS (NO) | 1999-09-15 | — | — | EP | claimed |
| WO-1998011922-A2 | METHOD | NYCOMED IMAGING AS (NO) | 1998-03-26 | — | — | WO | claimed |
| US-4535048-A | Toner for development of electrostatic charges | CANON KABUSHIKI KAISHA (JP) | 1985-08-13 | — | — | US | claimed |
| US-4057534-A | Method for preventing scale formation in a continuous ester-interchange reaction for production of polyesters | TEIJIN LIMITED (JA) | 1977-11-08 | — | — | US | claimed |