SCHEMBL1248016

SCHEMBL1248016

Cc1ccccc1C(Br)Br

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.54
ACHE P22303 2/20 0.47
TSHR P16473 1/20 0.47
ALDH1A1 P00352 3/20 0.43
ACP3 P15309 1/20 0.41
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
GAA P10253 1/20 0.38
OPRM1 P35372 4/20 0.38
OPRD1 P41143 3/20 0.38
OPRK1 P41145 3/20 0.38
OPRL1 P41146 3/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CYP3A4 P08684 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP2C9 P11712 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4430667 0.83 ESR1 (0.54) ESR1ACHETSHRALDH1A1ACP3
SCHEMBL16308863 0.81 ESR1 (0.52) ESR1ACHETSHRALDH1A1ACP3
SCHEMBL16308826 0.81 ESR1 (0.52) ESR1ACHETSHRALDH1A1ACP3
SCHEMBL30647211 0.81 ESR1 (0.52) ESR1ACHETSHRALDH1A1ACP3
SCHEMBL29403593 0.81 ESR1 (0.52) ESR1ACHETSHRALDH1A1ACP3
SCHEMBL624799 0.81 ESR1 (0.52) ESR1ACHETSHRALDH1A1ACP3
SCHEMBL4537404 0.80 ESR1 (0.41) ESR1ACHETSHRALDH1A1GAA
SCHEMBL6351769 0.79 ESR1 (0.50) ESR1ACHETSHRALDH1A1ACP3
SCHEMBL806254 0.79 ESR1 (0.50) ESR1ACHETSHRALDH1A1ACP3
SCHEMBL655520 0.78 CYP1A2 (0.43) ESR1TSHRALDH1A1SLC6A2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113999261-B O-dimethyl aromatic ring type diphosphine ligand compound and synthesis method thereof 浙江大学 2023-06-06 CN claimed
EP-2627172-A1 AN ANTIMICROBIAL COMPOSITION Agency For Science, Technology And Research (SG) 2013-08-21 EP claimed
US-20130210881-A1 ANTIMICROBIAL COMPOSITION AGENCY FOR SCIENCE ,TECHNOLOGY AND RESEARCH (SG) 2013-08-15 US claimed
WO-2012050531-A1 AN ANTIMICROBIAL COMPOSITION AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-04-19 WO claimed
EP-0242709-A2 Antagonists of specific excitatory amino acid neurotransmitter receptors NOVA PHARMACEUTICAL CORPORATION (US) 1987-10-28 EP claimed
JP-2311475-A None JP disclosed
CN-121045338-B Cyclic peptide targeting CAIX and preparation method and application thereof 原子高科股份有限公司 2026-05-19 CN disclosed
CN-119630790-A Novel LRP1 binding peptides 一丸自然美健有限公司 2025-03-14 CN disclosed
WO-2024243639-A1 AUTOPHAGY-INDUCING PEPTIDES THE FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH (AU) 2024-12-05 WO disclosed
CN-118995087-A Adhesive film and dicing film-die bonding film 株式会社力森诺科 2024-11-22 CN disclosed
CN-117940478-A Phenol resin, epoxy resin, curable resin composition, cured product, fiber-reinforced composite material, and fiber-reinforced resin molded article DIC株式会社 2024-04-26 CN disclosed
CN-117718084-A Grafted and hyperbranched mixed anion exchangers 戴安公司 2024-03-19 CN disclosed
US-4333932-A DIHYDROISOINDOLES, HYPOGLYCEMIC, ANTIDIABETIC PFIZER INC. (US) 1982-06-08 US disclosed
EP-0010896-B1 ORGANIC DIAMINE COMPOUNDS FOR USE AS ORAL HYPOGLYCEMIC AGENTS AND PHARMACEUTICAL COMPOSITIONS THEREOF PFIZER INC. (US) 1981-12-30 EP disclosed
US-4291114-A COMPRISING A PHOTOPOLYMERIZABLE LAYER OF A MONOMER AND A CATIONIC PROMOTER ON AN OLEOPHILIC SURFACE OF A COVERING MINNESOTA MINING AND MANUFACTURING CO. (US) 1981-09-22 US disclosed
EP-0035530-A1 IMAGEABLE, COMPOSITE DRY-TRANSFER SHEET. MINNESOTA MINING & MFG (US) 1981-09-16 EP disclosed
WO-1981000627-A1 IMAGEABLE,COMPOSITE DRY-TRANSFER SHEET MINNESOTA MINING & MFG (US) 1981-03-05 WO disclosed
US-4220650-A HYPOGLYCEMIC PFIZER INC. (US) 1980-09-02 US disclosed
US-4219648-A 7-[[Amino(1,3-dihydrobenzo[c]thienyl)acetyl]amino]cephalosporin derivatives RICHARDSON-MERRELL INC. (US) 1980-08-26 US disclosed
US-4178293-A Isoindolinyl derivatives ZOECON CORPORATION (US) 1979-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130210881-A1 ANTIMICROBIAL COMPOSITION NOD2, MPO, NACA ESR1 4312/4885ACHE 3877/4885TSHR 4102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.