Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712842 | 0.85 | MEN1 (0.40) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29738572 | 0.85 | MEN1 (0.40) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1248016 | 0.80 | ESR1 (0.54) | ESR1TSHRACHEALDH1A1GAA | |
| SCHEMBL5610691 | 0.80 | ESR1 (0.40) | ESR1TSHRACHENPC1RAB9A | |
| SCHEMBL6314140 | 0.79 | DHFR (0.45) | ESR1TSHRACHENPC1RAB9A | |
| SCHEMBL7647280 | 0.77 | ESR1 (0.41) | ESR1TSHRACHENPC1RAB9A | |
| SCHEMBL30354037 | 0.77 | ACHE (0.64) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30169568 | 0.77 | ACHE (0.64) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL197690 | 0.77 | ACHE (0.64) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5609719 | 0.76 | ESR1 (0.40) | ESR1TSHRACHENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638126-A1 | NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER | CRYSOPTIX K.K. (JP) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012064618-A1 | NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER | CRYSOPTIX KK (JP) | 2012-05-18 | — | — | WO | disclosed |