Pterocarpin

Pterocarpin

SCHEMBL1248057

COc1ccc2c(c1)OCC1c3cc4c(cc3OC21)OCO4

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 1.00
▸ TDP1 Q9NUW8 2/20 1.00
▸ MAPK1 P28482 1/20 1.00
▸ MAOA P21397 2/20 0.67
▸ MAOB P27338 2/20 0.67
▸ CYP3A4 P08684 2/20 0.67
▸ MEN1 O00255 3/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ DRD2 P14416 2/20 0.46
▸ DRD3 P35462 2/20 0.46
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ LMNA P02545 1/20 0.43
▸ ALDH1A1 P00352 2/20 0.42
▸ HPGD P15428 1/20 0.42
▸ USP2 O75604 1/20 0.40
▸ PTPN1 P18031 1/20 0.39
▸ ABCB1 P08183 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pterocarpin SCHEMBL29361907 1.00 MAPT (1.00) MAPTTDP1MAPK1MAOAMAOB
Pterocarpin SCHEMBL1248055 1.00 MAPT (1.00) MAPTTDP1MAPK1MAOAMAOB
Pterocarpin SCHEMBL3231566 0.92 MAPT (0.85) MAPTTDP1MAPK1MAOAMAOB
Homopterocarpin SCHEMBL12998414 0.89 MAPT (0.80) MAPTTDP1MAPK1MAOAMAOB
Homopterocarpin SCHEMBL12810803 0.89 MAPT (0.80) MAPTTDP1MAPK1MAOAMAOB
Homopterocarpin SCHEMBL12810250 0.89 MAPT (0.80) MAPTTDP1MAPK1MAOAMAOB
Homopterocarpin SCHEMBL31237481 0.89 MAPT (0.80) MAPTTDP1MAPK1MAOAMAOB
Homopterocarpin SCHEMBL29366996 0.89 MAPT (0.80) MAPTTDP1MAPK1MAOAMAOB
SCHEMBL12891389 0.83 MAPT (0.71) MAPTTDP1MAPK1MAOAMAOB
SCHEMBL18602053 0.83 MAPT (0.71) MAPTTDP1MAPK1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011066-A Preparation method of exogenous indian pterocarpus santalinus glycoside and application thereof in promoting germination of corn seeds 黑龙江八一农垦大学 2026-05-12 — — CN claimed
CN-119745895-A Traditional Chinese medicine monomer composition for treating rheumatoid arthritis and application thereof 中日友好医院(中日友好临床医学研究所) 2025-04-04 — — CN claimed
CN-115109809-B Midecarin is a biosynthesis method of (2) 南京中医药大学 2025-03-04 — — CN claimed
CN-113588857-B Quality detection method of radix sophorae tonkinensis and application thereof 中国人民解放军海军军医大学 2024-08-23 — — CN claimed
CN-114200040-B Content determination method for one-measurement-multiple-evaluation child type open throat sword spray 贵州三力制药股份有限公司 2023-12-08 — — CN claimed
CN-116600657-A Application of naringenin in improving quality of phlorizin taste 西姆莱斯有限公司 2023-08-15 — — CN claimed
CN-115869346-A Method for preparing gel for strengthening body by ultra-moxibustion 武代媛 2023-03-31 — — CN claimed
CN-115109809-A Biosynthesis method of santalin 南京中医药大学 2022-09-27 — — CN claimed
CN-115068588-A Application of active ingredients of gorse sinica maxim in preparation of anti-HPV (human papillomavirus) gel 江西康林药业有限公司 2022-09-20 — — CN claimed
CN-114437100-A Method for extracting santalin from sea sword beans and application of santalin 郑州师范学院 2022-05-06 — — CN claimed
EP-2295031-B1 Use of pterocarpans as anti-cellulite agents SYMRISE AG (DE) 2018-01-10 — — EP claimed
EP-2832371-B1 APPLICATION OF GASTRODIN AS SOLUBILIZER AND METHOD FOR PREPARING INJECTION OR POWDER FOR INJECTION KPC PHARMACEUTICALS INC (CN) 2017-02-01 — — EP claimed
CN-105434518-A Traditional Chinese medicine preparation for treating hepatitis CHANGSHU LEIYUNSHANG PHARMACEUTICAL CO LTD 2016-03-30 — — CN claimed
CN-104884035-A Hair colouring method employing a chromene or chroman dye, a particular organic compound, an oxidizing agent, an alkaline agent and a metal salt OREAL 2015-09-02 — — CN claimed
CN-104822424-A Oral compositions for enhancing skin tolerance following topical application of retinoid compounds INNEOV LAB 2015-08-05 — — CN claimed
EP-2832371-A1 APPLICATION OF GASTRODIN AS SOLUBILIZER AND METHOD FOR PREPARING INJECTION OR POWDER FOR INJECTION Kunming Pharmaceutical Corp. (CN) 2015-02-04 — — EP claimed
CN-103349007-A Agricultural composition containing antibiotics and plant source substances and application thereof HAINAN ZHENGYE ZHONGNONG HIGH TECHNOLOGY CO LTD 2013-10-16 — — CN claimed
EP-2295031-A2 Use of pterocarpans as anti-cellulite agents Symrise AG (DE) 2011-03-16 — — EP claimed
US-20110034486-A1 USE OF PTEROCARPANS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE GMBH & CO., KG (DE) 2011-02-10 — — US claimed
CN-101119711-A Methods of use of herbal compositions MEDIGREEN BIOTECHNOLOGY CORP (CN) 2008-02-06 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034486-A1 USE OF PTEROCARPANS AS ACTIVE ANTI-CELLULITE INGREDIENTS FABP4, PLIN1, CPT1B MAPT 4747/4885TDP1 1491/4885MAPK1 767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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