Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.50 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.46 |
| ▸ | AHCY | P23526 | 1/20 | 0.46 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.45 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12572425 | 1.00 | ABCB1 (0.51) | ABCB1P2RX3P2RX4P2RX2GSK3A | |
| SCHEMBL20820186 | 0.91 | P2RX3 (0.51) | ABCB1P2RX3P2RX4P2RX2GSK3A | |
| SCHEMBL12247692 | 0.90 | LMNA (0.47) | ABCB1P2RX3P2RX4P2RX2GSK3A | |
| SCHEMBL13151614 | 0.87 | LMNA (0.45) | P2RX3P2RX4P2RX2ADORA2ALMNA | |
| SCHEMBL17706607 | 0.87 | P2RX3 (0.49) | ABCB1P2RX3P2RX4P2RX2GSK3A | |
| SCHEMBL24829628 | 0.85 | NT5E (0.44) | ABCB1ADORA2ALMNAP2RY11 | |
| SCHEMBL17453217 | 0.85 | NT5E (0.44) | ABCB1ADORA2ALMNAP2RY11 | |
| SCHEMBL930787 | 0.85 | NT5E (0.44) | ABCB1ADORA2ALMNAP2RY11 | |
| SCHEMBL19777955 | 0.85 | NT5E (0.44) | ABCB1ADORA2ALMNAP2RY11 | |
| SCHEMBL930786 | 0.85 | NT5E (0.44) | ABCB1ADORA2ALMNAP2RY11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348029-A1 | Preparation of alkyl-substituted 2-deoxy-2-fluoro-d-ribofuranosyl pyrimidines and purines and their derivatives | Pharmasset, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |