Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | CETP | P11597 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249947 | 0.86 | LMNA (0.44) | SPHK1SPHK2CETPLMNATSHR | |
| SCHEMBL1630183 | 0.78 | SPHK1 (0.52) | SPHK1ALDH1A1SPHK2CETPCYP2D6 | |
| SCHEMBL12841553 | 0.78 | TSHR (0.35) | SPHK1SPHK2CETPTSHR | |
| SCHEMBL21428085 | 0.77 | SPHK1 (0.55) | SPHK1SPHK2CETPCYP2D6GMNN | |
| SCHEMBL15057401 | 0.77 | SPHK1 (0.55) | SPHK1SPHK2CETPCYP2D6GMNN | |
| SCHEMBL21636787 | 0.77 | SPHK1 (0.55) | SPHK1SPHK2CETPCYP2D6GMNN | |
| SCHEMBL21636792 | 0.75 | SPHK1 (0.52) | SPHK1SPHK2CETPCYP2D6GMNN | |
| Hydrochloric Acid SCHEMBL7612591 | 0.75 | SPHK1 (0.53) | SPHK1SPHK2CETPCYP2D6GMNN | |
| SCHEMBL28874947 | 0.74 | ALDH1A1 (0.34) | SPHK1ALDH1A1SPHK2CETPCYP3A4 | |
| SCHEMBL600713 | 0.74 | SPHK1 (0.52) | SPHK1ALDH1A1CETPCYP2D6GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103140469-B | Quaternary ammonium polyhydroxy compounds and their use in personal care compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-03-02 | — | — | CN | disclosed |
| EP-2621890-B1 | QUATERNARY AMMONIUM POLYHYDROXYL COMPOUNDS AND THEIR USE IN PERSONAL CARE COMPOSITIONS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-07-22 | — | — | EP | disclosed |
| EP-2621890-A1 | QUATERNARY AMMONIUM POLYHYDROXYL COMPOUNDS AND THEIR USE IN PERSONAL CARE COMPOSITIONS | Dow Global Technologies LLC (US) | 2013-08-07 | — | — | EP | disclosed |
| US-20130178542-A1 | MONOCATIONIC POLYHYDROXYL COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-07-11 | — | — | US | disclosed |
| CN-103140469-A | Quaternary ammonium polyhydroxy compounds and their use in personal care compositions | DOW GLOBAL TECHNOLOGIES LLC | 2013-06-05 | — | — | CN | disclosed |
| WO-2012050769-A1 | QUATERNARY AMMONIUM POLYHYDROXYL COMPOUNDS AND THEIR USE IN PERSONAL CARE COMPOSITIONS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178542-A1 | MONOCATIONIC POLYHYDROXYL COMPOUNDS | CUTA, PAH, PARG | SPHK1 4435/4885ALDH1A1 1105/4885SPHK2 4242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.