Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRR | Q9GZT4 | 3/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336410 | 0.95 | SRR (0.55) | SRRALPIPKMPTGS1XIAP | |
| SCHEMBL28230064 | 0.81 | ALDH1A1 (0.52) | SRRALPIPKMPTGS1XIAP | |
| SCHEMBL3980617 | 0.80 | KMT2A (0.55) | ALDH1A1CYP1A2NPC1RAB9AMMP8 | |
| SCHEMBL299389 | 0.80 | SLC7A5 (0.66) | SRRALPIPKMPTGS1XIAP | |
| SCHEMBL27632375 | 0.80 | SLC7A5 (0.66) | SRRALPIPKMPTGS1XIAP | |
| SCHEMBL979240 | 0.80 | KMT2A (0.55) | ALDH1A1CYP1A2NPC1RAB9AMMP8 | |
| SCHEMBL180159 | 0.80 | KMT2A (0.55) | ALDH1A1CYP1A2NPC1RAB9AMMP8 | |
| SCHEMBL5968413 | 0.80 | SLC7A5 (0.66) | SRRALPIPKMPTGS1XIAP | |
| SCHEMBL8583257 | 0.80 | ALPI (0.47) | SRRALPIPKMPTGS1XIAP | |
| Acetone SCHEMBL16013120 | 0.80 | ALPI (0.59) | SRRALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2811996-A1 | NEW PEDIATRIC USES OF CABAZITAXEL | Aventis Pharma S.A. (FR) | 2014-12-17 | — | — | EP | disclosed |
| WO-2013117683-A1 | NEW PEDIATRIC USES OF CABAZITAXEL | AVENTIS PHARMA S.A. (FR) | 2013-08-15 | — | — | WO | disclosed |
| WO-2012113897-A1 | ANTITUMORAL COMBINATION COMPRISING CABAZITAXEL AND CISPLATIN | AVENTIS PHARMA S.A. (FR) | 2012-08-30 | — | — | WO | disclosed |