Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRR | Q9GZT4 | 4/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.44 |
| ▸ | LAP3 | P28838 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | CPA3 | P15088 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL12482998 | 0.95 | SRR (0.50) | SRRALPIPKMPTGS1XIAP | |
| SCHEMBL5994752 | 0.81 | SRR (0.47) | SRRALPIPKMPTGS1XIAP | |
| SCHEMBL8218506 | 0.81 | METAP2 (0.48) | SRRANPEP | |
| SCHEMBL262278 | 0.81 | ALDH1A1 (0.55) | SRRCYP1A2SLC15A1LAP3LTA4H | |
| SCHEMBL979240 | 0.81 | KMT2A (0.55) | CYP1A2LTA4H | |
| SCHEMBL4219709 | 0.81 | ALDH1A1 (0.55) | SRRCYP1A2SLC15A1LAP3LTA4H | |
| SCHEMBL14543781 | 0.81 | CYP1A2 (0.48) | SRRALPIPKMPTGS1XIAP | |
| SCHEMBL180159 | 0.81 | KMT2A (0.55) | CYP1A2LTA4H | |
| SCHEMBL299389 | 0.81 | SLC7A5 (0.66) | SRRALPIPKMPTGS1XIAP | |
| SCHEMBL5968413 | 0.81 | SLC7A5 (0.66) | SRRALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190144406-A1 | CRYSTALLINE FORMS OF DIMETHOXY DOCETAXEL AND METHODS FOR PREPARING THE SAME | AVENTIS PHARMA SA (FR) | 2019-05-16 | — | — | US | disclosed |
| CN-105899491-B | 1-pyridazine-/triazin-3-yl-piperazine (-oxazine)/pyridine/pyrrolidine derivatives and compositions thereof for inhibiting SHP2 activity | 诺华股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-105899493-B | For inhibiting the active 1- of SHP2 (triazine -3- base/pyridazine -3- base)-piperazine (- piperazine) piperidine derivatives and combinations thereof | 诺华股份有限公司 | 2019-03-29 | — | — | CN | disclosed |
| US-10160739-B2 | Crystalline forms of dimethoxy docetaxel and methods for preparing the same | AVENTIS PHARMA S.A. (FR) | 2018-12-25 | — | — | US | disclosed |
| US-20180002302-A1 | CRYSTALLINE FORMS OF DIMETHOXY DOCETAXEL AND METHODS FOR PREPARING THE SAME | AVENTIS PHARMA S.A. (FR) | 2018-01-04 | — | — | US | disclosed |
| EP-2964212-A1 | CABAZITAXEL AND ITS USE FOR TREATING METASTATIC PROSTATE CANCERS | Aventis Pharma S.A. (FR) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014135524-A1 | CABAZITAXEL AND ITS USE FOR TREATING METASTATIC PROSTATE CANCERS | AVENTIS PHARMA S.A. (FR) | 2014-09-12 | — | — | WO | disclosed |
| WO-2012160568-A1 | PROCESS FOR PREPARING DOCETAXEL TRIHYDRATE POLYMORPH | SHILPA MEDICARE LIMITED (IN) | 2012-11-29 | — | — | WO | disclosed |
| WO-2012113897-A1 | ANTITUMORAL COMBINATION COMPRISING CABAZITAXEL AND CISPLATIN | AVENTIS PHARMA S.A. (FR) | 2012-08-30 | — | — | WO | disclosed |
| EP-2358693-A2 | PREPARATION OF DOCETAXEL | Dr. Reddy's Laboratories, Ltd. (IN) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010059916-A2 | PREPARATION OF DOCETAXEL | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-05-27 | — | — | WO | disclosed |