Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12856668 | 0.80 | ESR1 (0.40) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL26705390 | 0.79 | GPR84 (0.38) | CES2CES1 | |
| SCHEMBL6488214 | 0.77 | MAPT (0.46) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL30033048 | 0.77 | ALDH1A1 (0.45) | CA6KDM4ENPC1MAPTMAPK1 | |
| SCHEMBL12189899 | 0.77 | ALDH1A1 (0.45) | CA6KDM4ENPC1MAPTMAPK1 | |
| SCHEMBL155976 | 0.76 | CES2 (0.46) | ESR1ESR2CA3CA6CA5A | |
| SCHEMBL5510375 | 0.74 | ESR1 (0.42) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL8597374 | 0.74 | CES2 (0.44) | ESR1ESR2CA3CA6CA5A | |
| SCHEMBL14513491 | 0.71 | ALDH1A1 (0.37) | L3MBTL1 | |
| SCHEMBL25040847 | 0.71 | ESR1 (0.40) | ESR1ESR2CA3CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1544187-B1 | 1,7,8-TRIFLUORONAPHTHALENE-2-NAPHTHOL, AND METHODS FOR PRODUCING LIQUID CRYSTAL COMPOUNDS USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2011-02-16 | — | — | EP | claimed |
| US-9347002-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2016-05-24 | — | — | US | disclosed |
| CN-101550071-B | Manufacturing method of 1,7,8-trifluoro-2-naphthol | DAINIPPON INK & CHEMICALS | 2013-08-07 | — | — | CN | disclosed |
| CN-101550071-B | Manufacturing method of 1,7,8-trifluoro-2-naphthol | DAINIPPON INK & CHEMICALS | 2013-08-07 | — | — | CN | disclosed |
| EP-1544187-B1 | 1,7,8-TRIFLUORONAPHTHALENE-2-NAPHTHOL, AND METHODS FOR PRODUCING LIQUID CRYSTAL COMPOUNDS USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2011-02-16 | — | — | EP | disclosed |
| EP-1544187-B1 | 1,7,8-TRIFLUORONAPHTHALENE-2-NAPHTHOL, AND METHODS FOR PRODUCING LIQUID CRYSTAL COMPOUNDS USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2011-02-16 | — | — | EP | disclosed |
| EP-1544187-B1 | 1,7,8-TRIFLUORONAPHTHALENE-2-NAPHTHOL, AND METHODS FOR PRODUCING LIQUID CRYSTAL COMPOUNDS USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2011-02-16 | — | — | EP | disclosed |
| JP-2010248146-A | METHOD OF PRODUCING 1,7,8-TRIFLUORO-2-NAPHTHOL DERIVATIVE | SAGAMI CHEMICAL RESEARCH INSTITUTE | 2010-11-04 | — | — | JP | disclosed |
| JP-2010248145-A | 2-ACYLOXY-1,7,8-TRIFLUORONAPHTHALENE DERIVATIVE, AND METHOD OF PRODUCING THE SAME | SAGAMI CHEMICAL RESEARCH INSTITUTE | 2010-11-04 | — | — | JP | disclosed |
| JP-2010248144-A | 2-(2,3-DIFLUORO-6-VINYLPHENYL)ACETIC ACID DERIVATIVE, AND METHOD OF PRODUCING THE SAME | SAGAMI CHEMICAL RESEARCH INSTITUTE | 2010-11-04 | — | — | JP | disclosed |
| US-7214835-B2 | 1,7,8-Trifluoronaphthalene-2-naphthol, and method for producing liquid crystal compound using same | DAINIPPON INK & CHEMICALS, INC. (JP) | 2007-05-08 | — | — | US | disclosed |
| US-7214835-B2 | 1,7,8-Trifluoronaphthalene-2-naphthol, and method for producing liquid crystal compound using same | DAINIPPON INK & CHEMICALS, INC. (JP) | 2007-05-08 | — | — | US | disclosed |
| US-20060163537-A1 | 1,7,8-Trifluoronaphthalene-2-naphthol, and method for producing liquid crystal compound using same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20060163537-A1 | 1,7,8-Trifluoronaphthalene-2-naphthol, and method for producing liquid crystal compound using same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-07-27 | — | — | US | disclosed |
| CN-1684933-A | 1,7, 8-trifluoro-2-naphthol and method for preparing liquid crystal compound using the same | DAINIPPON INK & CHEMICALS CO L (JP) | 2005-10-19 | — | — | CN | disclosed |
| CN-1684933-A | 1,7, 8-trifluoro-2-naphthol and method for preparing liquid crystal compound using the same | DAINIPPON INK & CHEMICALS CO L (JP) | 2005-10-19 | — | — | CN | disclosed |
| EP-1544187-A1 | 1,7,8-TRIFLUORONAPHTHALENE-2-NAPHTHOL, AND METHOD FOR PRODUCING LIQUID CRYSTAL COMPOUND USING SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-06-22 | — | — | EP | disclosed |
| EP-1544187-A1 | 1,7,8-TRIFLUORONAPHTHALENE-2-NAPHTHOL, AND METHOD FOR PRODUCING LIQUID CRYSTAL COMPOUND USING SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-06-22 | — | — | EP | disclosed |
| JP-2004137258-A | 1, 7, 8-TRIFLUORO-2-NAPHTHOL AND METHOD FOR PRODUCING LIQUID CRYSTAL COMPOUND BY USING THE SAME | DAINIPPON INK & CHEM INC | 2004-05-13 | — | — | JP | disclosed |
| WO-2004029015-A1 | 1,7,8-TRIFLUORONAPHTHALENE-2-NAPHTHOL, AND METHOD FOR PRODUCING LIQUID CRYSTAL COMPOUND USING SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2004-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060163537-A1 | 1,7,8-Trifluoronaphthalene-2-naphthol, and method for producing liquid crystal compound using same | NOC2L, SNX2, NEFM | ESR1 4766/4885ESR2 4577/4885CYP17A1 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.