SCHEMBL124847

SCHEMBL124847

OB(O)c1cc(F)cc(F)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.45
CA12 O43570 1/20 0.45
CA9 Q16790 1/20 0.45
ORAI1 Q96D31 1/20 0.39
ORAI2 Q96SN7 1/20 0.39
ORAI3 Q9BRQ5 1/20 0.39
TRPV6 Q9H1D0 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
ENPP2 Q13822 5/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
MGLL Q99685 2/20 0.35
CA2 P00918 3/20 0.33
TSHR P16473 1/20 0.33
LPL P06858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6065331 0.85 CA12 (0.35) CA1CA12CA9ORAI1ORAI2
SCHEMBL29249836 0.85 CA12 (0.35) CA1CA12CA9ORAI1ORAI2
SCHEMBL675958 0.84 CA12 (0.57) CA1CA12CA9ORAI1ORAI2
SCHEMBL1289919 0.82 KDM4E (0.46) CA1CA12CA9ORAI1ORAI2
SCHEMBL2884582 0.82 CA1 (0.42) CA1CA12CA9ORAI1ORAI2
SCHEMBL30006611 0.82 KDM4E (0.46) CA1CA12CA9ORAI1ORAI2
SCHEMBL5524 0.82 ENPP2 (0.42) CA1CA12CA9ORAI1ORAI2
SCHEMBL248795 0.82 CA2 (0.42) CA1CA12CA9ORAI1ORAI2
SCHEMBL31590081 0.82 ENPP2 (0.42) CA1CA12CA9ORAI1ORAI2
SCHEMBL1158717 0.82 ENPP2 (0.38) CA1ORAI1ORAI2ORAI3TRPV6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3207 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4330229-B1 METHOD FOR PRODUCING PYRROLIDINE COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2025-12-17 EP claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-119798664-A Preparation process of adsorption material for treating textile printing and dyeing industry wastewater 广东江宇环保工程设备有限公司 2025-04-11 CN claimed
CN-119330924-A Preparation method of alkyl pyran 3, 5-difluorobenzene 石家庄市凯信电子材料有限公司 2025-01-21 CN claimed
US-20240228437-A1 METHOD FOR PRODUCING PYRROLIDINE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-07-11 US claimed
EP-4330229-A1 METHOD FOR PRODUCING PYRROLIDINE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2024-03-06 EP claimed
CN-117529470-A Method for producing pyrrolidine compounds 武田药品工业株式会社 2024-02-06 CN claimed
WO-2024016826-A1 6-POSITION SUBSTITUTED DIHYDROBENZO[E][1,2,3]OXATHIAZINE 2,2-DIOXIDE COMPOUND, PREPARATION THEREFOR, AND USE THEREOF 杭州市第七人民医院 2024-01-25 WO claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
US-20100040538-A1 Polymer Systems for Lung Volume Reduction Therapy CANADIAN IMPERIAL BANK OF COMMERCE (CA) 2010-02-18 US claimed
EP-2081946-A2 ADENOSINE DERIVATIVES FOR THE TREATMENT OF PAIN Biovitrum AB (publ) (SE) 2009-07-29 EP claimed
EP-2059227-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY Aeris Therapeutics, Inc. (US) 2009-05-20 EP claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed
WO-2008000745-A2 ADENOSINE DERIVATIVES FOR THE TREATMENT OF PAIN BIOVITRUM AB (PUBL) (SE) 2008-01-03 WO claimed
US-7037905-B2 Pharmaceutical use of boronic acids and esters thereof NOVO NORDISK A/S (DK) 2006-05-02 US claimed
US-20040053889-A1 Pharmaceutical use of boronic acids and esters thereof NOVO NORDISK A/S (DK) 2004-03-18 US claimed
WO-2003105860-A1 PHARMACEUTICAL USE OF BORONIC ACIDS AND ESTERS THEREOF NOVO NORDISK A/S (DK) 2003-12-24 WO claimed
US-20030211138-A1 Temperature control system for cutaneous photodynamic therapy SPECTRA SYSTEMS CORPORATION 2003-11-13 US claimed
WO-2003070315-A2 TEMPERATURE CONTROL SYSTEM FOR CUTANEOUS PHOTODYNAMIC THERAPY SPECTRA SYSTEMS CORPORATION (US) 2003-08-28 WO claimed