Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128893 | 0.89 | ENPP2 (0.46) | ENPP2ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL28490899 | 0.87 | ENPP2 (0.44) | ENPP2ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL124847 | 0.82 | CA1 (0.45) | ENPP2ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL974659 | 0.75 | TRPV6 (0.52) | ENPP2ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL8170579 | 0.75 | CES2 (0.31) | ENPP2ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL29636030 | 0.72 | ENPP2 (0.39) | ENPP2ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL13065321 | 0.72 | ENPP2 (0.39) | ENPP2ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL15810345 | 0.72 | CA2 (0.52) | ENPP2CA1CA2MGLLTSHR | |
| SCHEMBL14459947 | 0.71 | CES2 (0.38) | ENPP2ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL309397 | 0.71 | CA3 (0.52) | ENPP2CA1CA2MGLLTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7883785-B2 | 5'-mono-, 5',5''-bis- and 5',5'',5'''-tris-aryl/heteroaryl-functionalized tris-orthometallated organorhodium and organoiridium compounds; readily soluble triplet emitters | MERCK PATENT GMBH (DE) | 2011-02-08 | — | — | US | disclosed |