Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930873 | 0.77 | HPRT1 (0.47) | HPRT1KMT2AMAPTMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6935179 | 0.76 | HPRT1 (0.46) | HPRT1KMT2AMAPTMEN1ALDH1A1 | |
| Water SCHEMBL6931313 | 0.76 | HPRT1 (0.46) | HPRT1KMT2AMAPTMEN1ALDH1A1 | |
| Potassium Ion SCHEMBL6932912 | 0.67 | HPRT1 (0.45) | HPRT1KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL7858420 | 0.64 | LPAR2 (0.72) | KMT2AMAPTMEN1LPAR2LPAR3 | |
| SCHEMBL7858424 | 0.64 | LPAR2 (0.72) | KMT2AMAPTMEN1LPAR2LPAR3 | |
| SCHEMBL8768185 | 0.63 | HPRT1 (0.54) | HPRT1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL29258382 | 0.62 | LMNA (0.58) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL29258383 | 0.62 | LMNA (0.58) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL23909407 | 0.61 | HPRT1 (0.45) | HPRT1RAB9AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790344-B1 | Methods for treatment of disease-induced peripheral neuropathy and related conditions | SPECTRUM PHARMACEUTICALS INC (US) | 2011-02-23 | — | — | EP | disclosed |