Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | KDM4B | O94953 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375871 | 0.86 | HPRT1 (0.58) | HPRT1KDM4ETDP1TSHRPOLB | |
| SCHEMBL2913487 | 0.78 | HPRT1 (0.59) | HPRT1KMT2AKDM4AKDM4BKDM5C | |
| SCHEMBL7061691 | 0.75 | HPRT1 (0.59) | HPRT1ALDH1A1TSHRHSD17B10KDM4A | |
| SCHEMBL1672180 | 0.72 | HPRT1 (0.56) | HPRT1HSD17B10 | |
| SCHEMBL930873 | 0.72 | HPRT1 (0.47) | HPRT1ALDH1A1TDP1POLBCYP2C9 | |
| SCHEMBL21383159 | 0.71 | HPRT1 (0.48) | HPRT1ALDH1A1POLBKDM4AKDM4B | |
| SCHEMBL7451801 | 0.71 | HPRT1 (0.45) | HPRT1ALDH1A1TSHRKDM4AKDM4B | |
| Hydrochloric Acid SCHEMBL6935179 | 0.71 | HPRT1 (0.46) | HPRT1ALDH1A1TDP1POLBCYP2C9 | |
| Water SCHEMBL6931313 | 0.71 | HPRT1 (0.46) | HPRT1ALDH1A1TDP1POLBCYP2C9 | |
| SCHEMBL7405147 | 0.70 | HPRT1 (0.42) | HPRT1ALDH1A1KDM4ECYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |