Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.32 |
| ▸ | KDM4A | O75164 | 3/20 | 0.32 |
| ▸ | KDM4B | O94953 | 3/20 | 0.32 |
| ▸ | KDM5C | P41229 | 3/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451801 | 0.79 | HPRT1 (0.45) | HPRT1ALDH1A1IP6K1KDM5BKDM4A | |
| SCHEMBL21383159 | 0.79 | HPRT1 (0.48) | HPRT1ALDH1A1KDM5BKDM4AKDM4B | |
| SCHEMBL1866525 | 0.72 | HPRT1 (0.58) | HPRT1ALDH1A1KDM5BKDM4AKDM4B | |
| SCHEMBL16542399 | 0.71 | ALDH1A1 (0.35) | ALDH1A1IP6K1KDM5BKDM4AKDM4B | |
| SCHEMBL8768185 | 0.71 | HPRT1 (0.54) | HPRT1ALDH1A1KDM5BKDM4AKDM4B | |
| SCHEMBL2913487 | 0.70 | HPRT1 (0.59) | HPRT1KDM5BKDM4AKDM4BKDM5C | |
| SCHEMBL7375871 | 0.69 | HPRT1 (0.58) | HPRT1SMN1; SMN2ALOX15TSHR | |
| SCHEMBL7405147 | 0.67 | HPRT1 (0.42) | HPRT1ALDH1A1LMNAADORA2ARAB9A | |
| SCHEMBL7061691 | 0.67 | HPRT1 (0.59) | HPRT1ALDH1A1KDM5BKDM4AKDM4B | |
| Hydrochloric Acid SCHEMBL5489581 | 0.67 | HPRT1 (0.37) | HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317407-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | Seattle Children's Hospital (dba Seattle Children's Research Institute) | 2021-10-14 | — | — | US | disclosed |