Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1248610 | 1.00 | NPSR1 (0.54) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL7552831 | 1.00 | NPSR1 (0.54) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL11168141 | 0.83 | NPSR1 (0.43) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL8778884 | 0.83 | NPSR1 (0.43) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL8778882 | 0.83 | NPSR1 (0.43) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10959675 | 0.83 | NPSR1 (0.43) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9666690 | 0.83 | NPSR1 (0.43) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6023236 | 0.80 | NPSR1 (0.52) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6023238 | 0.80 | NPSR1 (0.52) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9517913 | 0.79 | ATM (0.59) | NPSR1HCAR2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615879-B1 | PROCESS FOR THE PRODUCTION OF 9-CIS RETINOIC ACID | GLAXO GROUP LTD (GB) | 2014-01-29 | — | — | EP | claimed |
| CN-1323071-C | Process for the production of 9-cis retinoic acid. | HOFFMANN LA ROCHE (CH) | 2007-06-27 | — | — | CN | claimed |
| CN-1771227-A | Process for the production of 9-cis retinoic acid. | HOFFMANN LA ROCHE (CH) | 2006-05-10 | — | — | CN | claimed |
| US-7015353-B2 | Process for the production of 9-(Z)-retinoic acid | HOFFMANN-LA ROCHE INC. (US) | 2006-03-21 | — | — | US | claimed |
| EP-1615879-A1 | PROCESS FOR THE PRODUCTION OF 9-CIS RETINOIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 2006-01-18 | — | — | EP | claimed |
| US-20040235951-A1 | Process for the production of 9-(Z)-retinoic acid | BASILEA PHARMACEUTICA INTERNATIONAL LTD. (CH) | 2004-11-25 | — | — | US | claimed |
| WO-2004089887-A1 | PROCESS FOR THE PRODUCTION OF 9-CIS RETINOIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 2004-10-21 | — | — | WO | claimed |
| EP-0371264-A2 | Phosphonate reagent compositions and methods of making same | LOYOLA UNIVERSITY OF CHICAGO (US) | 1990-06-06 | — | — | EP | claimed |
| WO-2024006776-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| CN-117098749-A | [11C] Labeled acyclic retinoids, central nervous system activators and methods for their manufacture | 国立研究开发法人国立长寿医疗研究中心 | 2023-11-21 | — | — | CN | disclosed |
| WO-2022107865-A1 | [11C]-LABELLED ACYCLIC RETINOID, CENTRAL NERVOUS SYSTEM ACTIVATOR, AND PRODUCTION METHODS FOR SAME | 国立研究開発法人国立長寿医療研究センター | 2022-05-27 | — | — | WO | disclosed |
| CN-112898147-B | Method for asymmetric synthesis of (13R,14S) -13-hydroxy-14-methylhexadecanoic acid | 中国农业大学 | 2022-02-11 | — | — | CN | disclosed |
| US-11116212-B2 | Carbonyl containing compounds for controlling and repelling Cimicidae populations | SEMIOSBIO TECHNOLOGIES INC. (CA) | 2021-09-14 | — | — | US | disclosed |
| US-8889660-B2 | Methods for treating obesity or an obesity related condition | CASE WESTERN RESERVE UNIVERSITY (US) | 2014-11-18 | — | — | US | disclosed |
| US-5296505-A | Reacting dithianepropenol with ethynyl-beta-ionol in presence of organomagnesium compound, hydrogenating triple bond, reducing diol with low-valency titanium | L'OREAL (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5061819-A | Methods for synthesizing phosphonate reagents and retinoids | LOYOLA UNIVERSITY OF CHICAGO (US) | 1991-10-29 | — | — | US | disclosed |
| EP-0371264-A2 | Phosphonate reagent compositions and methods of making same | LOYOLA UNIVERSITY OF CHICAGO (US) | 1990-06-06 | — | — | EP | disclosed |
| US-4916250-A | Phosphonate reagent compositions | LOYOLA UNIVERSITY OF CHICAGO (US) | 1990-04-10 | — | — | US | disclosed |
| EP-0010208-B1 | PHARMACEUTICAL COMPOSITION CONTAINING ALL-E- OR 13-Z-7,8-DEHYDRO-RETINOIC ACID AND PROCESS FOR ITS PREPARATION | BASF Aktiengesellschaft (DE) | 1982-08-11 | — | — | EP | disclosed |
| EP-0010208-A1 | Pharmaceutical composition containing all-E- or 13-Z-7,8-dehydro-retinoic acid and process for its preparation | BASF Aktiengesellschaft (DE) | 1980-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235951-A1 | Process for the production of 9-(Z)-retinoic acid | RARA, RARB, RARG | NPSR1 4545/4885HCAR2 1132/4885ALDH1A1 1043/4885 |
| US-11116212-B2 | Carbonyl containing compounds for controlling and repelling Cimicidae populations | DDT, AOC1, EGLN1 | NPSR1 3408/4885HCAR2 2072/4885ALDH1A1 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.