Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2446838 | 0.79 | PSIP1 (0.52) | PSIP1SMN1; SMN2CCR5HTR6HSD11B1 | |
| SCHEMBL17527530 | 0.79 | HTR6 (0.46) | PSIP1SMN1; SMN2HTR6TDP1ALDH1A1 | |
| SCHEMBL835333 | 0.76 | PSIP1 (0.44) | PSIP1SMN1; SMN2CCR5HSD11B1TSHR | |
| SCHEMBL1476603 | 0.76 | PSIP1 (0.44) | PSIP1SMN1; SMN2CCR5HSD11B1TSHR | |
| SCHEMBL835334 | 0.76 | PSIP1 (0.44) | PSIP1SMN1; SMN2CCR5HSD11B1TSHR | |
| SCHEMBL21766568 | 0.72 | PSIP1 (0.43) | PSIP1SMN1; SMN2CCR5HSD11B1LARS1 | |
| SCHEMBL2443658 | 0.72 | PSIP1 (0.54) | PSIP1SMN1; SMN2CCR5HTR6HSD11B1 | |
| SCHEMBL3635347 | 0.72 | PSIP1 (0.58) | PSIP1SMN1; SMN2HTR6HSD11B1TDP1 | |
| SCHEMBL21708862 | 0.70 | HTR6 (0.46) | PSIP1SMN1; SMN2HTR6TDP1ALDH1A1 | |
| SCHEMBL12486139 | 0.70 | HTR6 (0.46) | PSIP1SMN1; SMN2HTR6TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973024-B2 | 24-sulfoximine vitamin D3 compounds | Cyctochroma Inc. (CA) | 2011-07-05 | — | — | US | disclosed |