Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12486444 | 0.73 | GAA (0.37) | TAAR1GAAMEN1KMT2AHTR1A | |
| Hydrochloric Acid SCHEMBL12485366 | 0.72 | GAA (0.36) | TAAR1GAAMEN1KMT2AHTR1A | |
| SCHEMBL4709300 | 0.72 | SLC22A1 (0.59) | HTR2A | |
| SCHEMBL12485294 | 0.72 | SLC22A1 (0.42) | GAAMEN1KMT2ASLC6A3DRD2 | |
| SCHEMBL12486252 | 0.72 | GAA (0.38) | TAAR1GAAMEN1KMT2AHTR1A | |
| SCHEMBL12485441 | 0.71 | SLC22A1 (0.43) | TAAR1GAAMEN1KMT2ADRD2 | |
| SCHEMBL9531248 | 0.71 | TAAR1 (0.52) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL3312684 | 0.71 | KMT2A (0.37) | TAAR1KMT2AHTR1ADRD2HTR7 | |
| SCHEMBL12486539 | 0.70 | BCHE (0.45) | MEN1KMT2A | |
| SCHEMBL12761042 | 0.70 | PARP1 (0.37) | TAAR1HTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012114252-A1 | NOVEL INDOLE AND PYRROLOPYRIDINE AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-08-30 | — | — | WO | disclosed |