Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3312684 | 0.78 | KMT2A (0.37) | TAAR1DRD2HTR1AHTR7PRCP | |
| SCHEMBL12761042 | 0.77 | PARP1 (0.37) | TAAR1DRD2HTR1AHTR7PRCP | |
| SCHEMBL9210176 | 0.76 | GID4 (0.49) | TAAR1DRD2PRCPDRD3SLC22A1 | |
| SCHEMBL4709300 | 0.74 | SLC22A1 (0.59) | PRCPSLC22A1 | |
| SCHEMBL4709088 | 0.73 | MAOA (0.41) | TAAR1DRD2HTR1AHTR7DRD3 | |
| SCHEMBL9534305 | 0.73 | TAAR1 (0.55) | TAAR1 | |
| SCHEMBL12485441 | 0.73 | SLC22A1 (0.43) | TAAR1DRD2PRCPSLC22A1 | |
| SCHEMBL21248576 | 0.72 | KMT2A (0.58) | — | |
| SCHEMBL12486539 | 0.72 | BCHE (0.45) | — | |
| SCHEMBL330217 | 0.71 | PRCP (0.62) | PRCPSLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575362-A1 | TETRAHYDROTHIENO(2,3-c)PYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL APPLICATION | Smithkline Beecham Farmaceutici S.p.A. (IT) | 1993-12-29 | — | — | EP | disclosed |
| WO-1992015592-A1 | TETRAHYDROTHIENO(2,3-c)PYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL APPLICATION | SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) | 1992-09-17 | — | — | WO | disclosed |