Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12486444 | 0.85 | GAA (0.37) | SLC22A1PRCPGAADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL12485366 | 0.84 | GAA (0.36) | SLC22A1PRCPGAADRD2DRD4 | |
| SCHEMBL12486252 | 0.83 | GAA (0.38) | SLC22A1PRCPGAADRD2DRD4 | |
| SCHEMBL12485441 | 0.79 | SLC22A1 (0.43) | SLC22A1PRCPGAADRD2DRD4 | |
| SCHEMBL4709300 | 0.77 | SLC22A1 (0.59) | SLC22A1PRCPKDM1A | |
| SCHEMBL12485686 | 0.76 | GID4 (0.46) | SLC22A1PRCPGAADRD2DRD4 | |
| SCHEMBL12486539 | 0.74 | BCHE (0.45) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL12485208 | 0.74 | SLC22A1 (0.37) | SLC22A1PRCPGAADRD2DRD4 | |
| SCHEMBL12485377 | 0.74 | HTR2B (0.42) | SLC22A1PRCPDRD4KDM4EMAPT | |
| SCHEMBL12485294 | 0.73 | SLC22A1 (0.42) | SLC22A1PRCPGAADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012114252-A1 | NOVEL INDOLE AND PYRROLOPYRIDINE AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-08-30 | — | — | WO | disclosed |