Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906610 | 0.88 | HDAC3 (0.46) | CCR6PAX8LTA4HALDH1A1HDAC1 | |
| SCHEMBL8622951 | 0.84 | ALOX5 (0.48) | CCR6PAX8LTA4HL3MBTL1HDAC1 | |
| SCHEMBL6618522 | 0.83 | MAPT (0.49) | CCR6PAX8L3MBTL1HDAC1HDAC2 | |
| SCHEMBL9879981 | 0.83 | MAPT (0.49) | CCR6PAX8L3MBTL1HDAC1HDAC2 | |
| SCHEMBL6951407 | 0.82 | HTT (0.44) | CCR6PAX8LTA4HALDH1A1HCAR2 | |
| SCHEMBL7305614 | 0.82 | LTA4H (0.41) | CCR6PAX8LTA4HALDH1A1L3MBTL1 | |
| SCHEMBL667448 | 0.81 | CCR6 (0.42) | CCR6PAX8LTA4HALDH1A1L3MBTL1 | |
| SCHEMBL6253004 | 0.80 | KCNH2 (0.43) | SLC6A2SLC6A3ALOX5 | |
| SCHEMBL7739753 | 0.79 | CCR6 (0.41) | CCR6PAX8LTA4HALDH1A1L3MBTL1 | |
| SCHEMBL8989023 | 0.79 | CCR6 (0.41) | CCR6PAX8LTA4HALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2684039-A2 | PEPTIDE DEFORMYLASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012122450-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-09-13 | — | — | WO | disclosed |