Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879981 | 0.99 | MAPT (0.49) | ALOX5MAPTRXFP1HDAC2HDAC8 | |
| SCHEMBL6618522 | 0.99 | MAPT (0.49) | ALOX5MAPTRXFP1HDAC2HDAC8 | |
| SCHEMBL2906610 | 0.95 | HDAC3 (0.46) | ALOX5MAPTRXFP1HDAC2HDAC8 | |
| SCHEMBL6951407 | 0.89 | HTT (0.44) | ALOX5MAPTRXFP1HDAC2HDAC8 | |
| SCHEMBL667448 | 0.85 | CCR6 (0.42) | HDAC2HDAC8HDAC6HDAC1HDAC3 | |
| SCHEMBL8989071 | 0.85 | L3MBTL1 (0.35) | ALOX5HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL12487487 | 0.84 | CCR6 (0.36) | ALOX5HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL7095566 | 0.84 | HDAC2 (0.45) | ALOX5HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL7081392 | 0.84 | LSS (0.37) | ALOX5HTTTOP1CCR6PAX8 | |
| SCHEMBL8989023 | 0.84 | CCR6 (0.41) | HDAC2HDAC8HDAC6HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801271-A | CHEMICAL INTERMEDIATES FOR ANTIDEPRESSANTS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0860426-A1 | 7-(n-substituted amino)-2-phenylheptanoic acid derivative and process for manufacturing the same | Takasago International Corporation (JP) | 1998-08-26 | — | — | EP | disclosed |