Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 3/20 | 0.39 |
| ▸ | Q9HBH1 | 10/20 | 0.39 | |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12487092 | 0.92 | PDF (0.48) | CFDPDF | |
| SCHEMBL12487555 | 0.89 | CFD (0.37) | F2CFDPDF | |
| SCHEMBL12487738 | 0.87 | CFD (0.38) | F2CFDPDF | |
| SCHEMBL27955613 | 0.84 | PDF (0.43) | F2PDFMMP2MMP9MMP12 | |
| SCHEMBL12487979 | 0.84 | PDF (0.43) | F2PDFMMP2MMP9MMP12 | |
| SCHEMBL27955615 | 0.82 | PDF (0.52) | F2PDFMMP2MMP9MMP12 | |
| SCHEMBL12487488 | 0.82 | PDF (0.52) | F2PDFMMP2MMP9MMP12 | |
| SCHEMBL12487608 | 0.80 | F2 (0.42) | F2PDFMMP2MMP9MMP12 | |
| SCHEMBL27955608 | 0.80 | F2 (0.42) | F2PDFMMP2MMP9MMP12 | |
| SCHEMBL12487495 | 0.79 | PDF (0.60) | F2PDF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2684039-A2 | PEPTIDE DEFORMYLASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012122450-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-09-13 | — | — | WO | disclosed |