Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 7/20 | 0.38 | |
| ▸ | DPP4 | P27487 | 11/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12487507 | 0.87 | PDF (0.50) | PDFDPP4CTSS | |
| SCHEMBL12487693 | 0.85 | PDF (0.49) | PDFDPP4F2 | |
| SCHEMBL12487874 | 0.85 | PDF (0.55) | PDFDPP4F2 | |
| SCHEMBL12487648 | 0.84 | PDF (0.36) | PDFDPP4F2 | |
| SCHEMBL12487769 | 0.82 | PDF (0.41) | PDFF2 | |
| SCHEMBL12487024 | 0.79 | ATM (0.37) | PDFDPP4F2CTSS | |
| SCHEMBL12487738 | 0.79 | CFD (0.38) | PDFDPP4F2 | |
| SCHEMBL12486957 | 0.76 | CTSS (0.45) | DPP4F2CTSS | |
| SCHEMBL12486756 | 0.74 | F2 (0.34) | PDFF2 | |
| SCHEMBL27955616 | 0.72 | PDF (0.63) | PDFDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2684039-A2 | PEPTIDE DEFORMYLASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012122450-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-09-13 | — | — | WO | disclosed |