Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14648164 | 0.90 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL2196617 | 0.90 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL2179610 | 0.86 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL12488611 | 0.86 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL27879648 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL14648250 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL2196503 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL2195941 | 0.77 | HSD17B10 (0.53) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL2193840 | 0.77 | HSD17B10 (0.53) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL2175697 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082077-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |