Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1860093 | 0.92 | PKM (0.38) | KMT2APRKDCSMN1; SMN2PKMTSHR | |
| SCHEMBL1305247 | 0.85 | GRM5 (0.33) | MAPTKMT2ATYRSMN1; SMN2PKM | |
| SCHEMBL12409136 | 0.84 | KDM4E (0.41) | KDM4EMAPTMAPK1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2045087 | 0.80 | ORAI1 (0.35) | KDM4EMAPTORAI1 | |
| SCHEMBL27964629 | 0.79 | ORAI1 (0.34) | KDM4EMAPTORAI1 | |
| SCHEMBL981067 | 0.79 | MAPT (0.34) | MAPTMAPK1KMT2ATYRSMN1; SMN2 | |
| SCHEMBL3695100 | 0.78 | RECQL (0.44) | KDM4EMAPTORAI1SMN1; SMN2PKM | |
| SCHEMBL2038180 | 0.77 | SYK (0.42) | MAPTKMT2AMEN1HPGDORAI1 | |
| SCHEMBL1466705 | 0.76 | DDB1 (0.33) | ORAI1TSHR | |
| SCHEMBL1860700 | 0.76 | AKR1B1 (0.33) | MAPTMAPK1TYRSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130137876-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2013-05-30 | — | — | US | disclosed |
| US-8362257-B2 | Nitrogen-containing heterocyclic compound and pest control agent | NIPPON SODA CO., LTD. (JP) | 2013-01-29 | — | — | US | disclosed |
| US-20110166358-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137876-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PEST CONTROL AGENT | CBR3, CBR1, NOXO1 | KDM4E 1194/4885MAPT 4670/4885MAPK1 2120/4885 |
| US-20110166358-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PEST CONTROL AGENT | CBR3, CBR1, NOXO1 | KDM4E 1194/4885MAPT 4670/4885MAPK1 2120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.